glucosaminylmuramyl- 2- alanine- D- isoglutamine

the epitope of peptidoglycan

Also Known As:

glucosaminyl muramyl dipeptide; glucosaminyl-mdp; glucosaminyl-muramyl-dipeptide; glucosaminylmuramyl dipeptide

Networked: 21 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Amino Sugars: 110
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - glucosaminylmuramyl-2-alanine-D-isoglutamine: 21
- Sugar Acids: 4
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - glucosaminylmuramyl-2-alanine-D-isoglutamine: 21
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - glucosaminylmuramyl-2-alanine-D-isoglutamine: 21

Experts

1.	Andronova, T M: 4 articles (01/2021 - 12/2005)
2.	Kalyuzhin, O V: 2 articles (01/2021 - 12/2020)
3.	Karaulov, A V: 2 articles (01/2021 - 12/2020)
4.	Andronova, Tatiana M: 2 articles (04/2010 - 09/2006)
5.	Komaleva, Ravilya L: 2 articles (04/2010 - 09/2006)
6.	Nesmeyanov, Vladimir A: 2 articles (04/2010 - 09/2006)
7.	Petrova, Elena E: 2 articles (04/2010 - 09/2006)
8.	Simonova, Maria A: 2 articles (04/2010 - 09/2006)
9.	Valyakina, Tatiana I: 2 articles (04/2010 - 09/2006)
10.	Gigani, Olga B: 1 article (01/2022)

Related Diseases

1.	Respiratory Tract Infections (Respiratory Tract Infection) 01/10/2021 - "All of the above has prompted revisiting the previously obtained evidence of the efficacy of glucosaminylmuramyl dipeptide (GMDP) as a NOD2 agonist in treatment/prevention of respiratory infections. " 12/15/2020 - "First of all, attention should be paid to glucosaminylmuramyl dipeptide, approved for clinical use in Russia and a number of post-Soviet countries for the complex treatment and prevention of acute and recurrent respiratory infections. " 11/01/2014 - "It is established that preventive immune correction with lysates of bacteria or glucosaminyl muramyl dipeptide in aggregate with vitamin mineral complex results in statistically significant decreasing of rate of respiratory infections and dramatic decreasing of direct and indirect costs of treatment of infectious diseases of respiratory ways. "
2.	Tularemia 05/01/1985 - "[Experimental multifactorial study of the effect of doxycycline and glucosaminylmuramyl dipeptide on the primary immunologic response to antigens of a tularemia vaccine strain]." 05/01/1985 - "The effect of the combined use of doxycycline and glucosaminylmuramyl dipeptide (GMDP) on the primary immune response to antigens of tularemia vaccine was studied on CBA male mice with the use of the multifactorial design of experiment. "
3.	Neutropenia 08/01/1999 - "Study on the reduction of chemotherapy induced neutropenia in mice using glucosaminylmuramyl dipeptide."
4.	Inflammation (Inflammations) 01/11/2023 - "The aim of this investigation was to study the dynamic changes in the gene expression of A20 and ATF3, the inflammation suppressors, against the background of the expression of the genes of the innate immunity receptors TLR4 and NOD2 and the pro-inflammatory cytokine TNF-α under the influence of TLR4 and NOD2 agonists, lipopolysaccharide (LPS) and glucosaminylmuramyl dipeptide (GMDP). "
5.	Asthma (Bronchial Asthma) 01/27/2022 - "In the present study, we analyzed cellular and humoral factors in a standard mouse model of OVA-induced asthma modified by 5-fold intraperitoneal injection of bacterial cell wall fragments of glucosaminylmuramyl dipeptide (GMDP) 5 μg/animal or 1 μg lipopolysaccharide (LPS) per animal for 5 days before sensitization by ovalbumin (OVA). "

Related Drugs and Biologics

1.	Lipopolysaccharides
2.	Vaccines
3.	Cytokines
4.	Ovalbumin
5.	Doxycycline (Periostat)
6.	Antigens
7.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
8.	Cisplatin (Platino)
9.	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
10.	Vitamins

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Intraperitoneal Injections
3.	Therapeutics