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4-hydroxyhexenal

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - 4-hydroxyhexenal: 6

Experts

1.	Canuto, R A: 1 article (10/2016)
2.	Maggiora, M: 1 article (10/2016)
3.	Monacelli, F: 1 article (10/2016)
4.	Muzio, G: 1 article (10/2016)
5.	Oraldi, M: 1 article (10/2016)
6.	Ricci, M: 1 article (10/2016)
7.	Traverso, N: 1 article (10/2016)
8.	Bousamra, Michael: 1 article (02/2014)
9.	Fu, Xiao-An: 1 article (02/2014)
10.	Knipp, Ralph J: 1 article (02/2014)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 10/01/2016 - "4-Hydroxyhexenal and 4-hydroxynonenal are mediators of the anti-cachectic effect of n-3 and n-6 polyunsaturated fatty acids on human lung cancer cells." 02/01/2014 - "The concentrations of 2-butanone, 2-hydroxyacetaldehyde, 3-hydroxy-2-butanone, and 4-hydroxyhexenal (4-HHE) in the exhaled breath of lung cancer patients (n = 97) were significantly higher than in the exhaled breath of healthy smoker and nonsmoker controls (n = 88) and patients with benign pulmonary nodules (n = 32). "
2.	Macular Degeneration (Age-Related Maculopathy) 05/01/2008 - "In retinal sections from three monkeys with macular degeneration, regardless of their size, drusen were consistently positive with immunohistochemical labeling against protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal, end products of non-enzymatic oxidation of n-6 and n-3 polyunsaturated fatty acids, respectively. "
3.	Inflammation (Inflammations) 07/29/2011 - "Herein we show that the inflammation-derived cholesterol 5,6-secosterol aldehydes, atheronal-A (KA) and -B (ALD), but not the polyunsaturated fatty acid (PUFA)-derived aldehydes 4-hydroxynonenal (HNE) and 4-hydroxyhexenal (HHE), induce misfolding of wild-type p53 into an amyloidogenic form that binds thioflavin T and Congo red dyes but cannot bind to a consensus DNA sequence. "
4.	Chromosome Aberrations (Chromosome Abnormalities) 12/01/1993 - "The induction of chromosomal aberrations was significantly elevated at concentrations of > or = 10 microM and 10 microM for 4-hydroxyhexenal and 4-hydroxyundecenal, respectively. "
5.	Alzheimer Disease (Alzheimer's Disease) 06/01/2012 - "Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression."

Related Drugs and Biologics

1.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
2.	4-hydroxy-2-nonenal (4-hydroxynonenal)
3.	Retinaldehyde (Retinal)
4.	Proteins (Proteins, Gene)
5.	Coloring Agents (Dyes)
6.	Congo Red
7.	Cholesterol
8.	Aldehydes
9.	Acetoin
10.	atheronal-A