galactosylxylosylprotein 3-beta-galactosyltransferase

Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates); catalyzes the reaction of UDPgalactose & 4-beta-D-(galactosyl-O-beta-D-xylosylprotein to yield UDP & 3-beta-D-galactosyl-O-beta-D-xylosylprotein

Also Known As:

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Calzavara-Pinton, Piergiacomo: 1 article (03/2015)
2.	Chiarelli, Nicola: 1 article (03/2015)
3.	Colombi, Marina: 1 article (03/2015)
4.	Dordoni, Chiara: 1 article (03/2015)
5.	Quinzani, Stefano: 1 article (03/2015)
6.	Ritelli, Marco: 1 article (03/2015)
7.	Traversa, Michele: 1 article (03/2015)
8.	Venturini, Marina: 1 article (03/2015)
9.	Zoppi, Nicoletta: 1 article (03/2015)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 09/24/1981 - "Galactosyltransferase II in detection of pancreatic cancer." 01/01/1981 - "Galactosyltransferase II: role in the diagnosis of pancreatic carcinoma." 01/01/1988 - "The clinical usefulness of tissue polypeptide antigen, galactosyltransferase II and pancreatic oncofetal antigen was evaluated in detecting pancreatic cancer and in differentiating this malignancy from chronic pancreatitis and other diseases (mainly of the liver and biliary tract) which may enter in differential diagnosis. "
2.	Chronic Pancreatitis 01/01/1988 - "The clinical usefulness of tissue polypeptide antigen, galactosyltransferase II and pancreatic oncofetal antigen was evaluated in detecting pancreatic cancer and in differentiating this malignancy from chronic pancreatitis and other diseases (mainly of the liver and biliary tract) which may enter in differential diagnosis. "
3.	Neoplasms (Cancer) 01/01/1988 - "The clinical usefulness of tissue polypeptide antigen, galactosyltransferase II and pancreatic oncofetal antigen was evaluated in detecting pancreatic cancer and in differentiating this malignancy from chronic pancreatitis and other diseases (mainly of the liver and biliary tract) which may enter in differential diagnosis. "
4.	Spondyloepimetaphyseal Dysplasia With Joint Laxity 03/01/2015 - "Mutations in B3GALT6, encoding the galactosyltransferase II (GalT-II) involved in the synthesis of the glycosaminoglycan (GAG) linkage region of proteoglycans (PGs), have recently been associated with a spectrum of connective tissue disorders, including spondyloepimetaphyseal dysplasia with joint laxity type 1 (SEMDJL1) and Ehlers-Danlos-like syndrome. "

Related Drugs and Biologics

1.	Tissue Polypeptide Antigen
2.	Proteoglycans (Proteoglycan)
3.	Glycosaminoglycans
4.	oncofetal antigens