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cycloprotobuxine A
RN given refers to (3beta,5alpha,20S)-isomer; from Buxus microphyyla Sieb
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
cycloprotobuxine A: 3
Related Diseases
1.
Atrial Fibrillation
05/01/1997 - "
To study the effects of cycloprotobuxine-A (Cyc-A) on atrial fibrillation.
"
05/01/1997 - "
Effects of cycloprotobuxine-A on atrial fibrillation.
"
2.
Cardiac Arrhythmias (Arrythmia)
11/10/1992 - "
These results suggested that cycloprotobuxine-A could have a low affinity for resting Na+ channels but a much higher affinity for activated and/or inactivated Na+ channels, and that the use-, frequency- and voltage-dependent effects of cycloprotobuxine-A on Vmax may play an important role in preventing the development of cardiac arrhythmias.
"
05/01/1992 - "
Protective effect of cycloprotobuxine-A against cardiac arrhythmias induced by ouabain.
"
Related Drugs and Biologics
1.
Ouabain (G Strophanthin)