selenophosphate synthetase
involved in selenium metabolism; gamma-phosphate of ATP is transferred to HSe resulting in formation of monoselenophosphate; amino acid sequence in first source
Networked: 7
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Carlson, Bradley A:
1 article
(01/2022)
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2. | Chang, Chong Bum:
1 article
(01/2022)
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3. | Chang, Moon Jong:
1 article
(01/2022)
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4. | Gladyshev, Vadim N:
1 article
(01/2022)
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5. | Hatfield, Dolph L:
1 article
(01/2022)
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6. | Jung, Jisu:
1 article
(01/2022)
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7. | Kang, Donghyun:
1 article
(01/2022)
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8. | Kang, Seung-Baik:
1 article
(01/2022)
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9. | Kim, Jin-Hong:
1 article
(01/2022)
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10. | Lee, Byeong Jae:
1 article
(01/2022)
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Related Diseases
1. | Neoplasms (Cancer)
10/01/2006
- " Therefore, to gain insight into the mechanisms underlying cancer prevention by selenium, we investigated sps1, one of the two human selenophosphate synthetase genes for its role in cancer cell's response to ionizing radiation. " 01/01/2020
- " The micronutrient selenium is incorporated via the selenocysteine biosynthesis pathway into the rare amino acid selenocysteine, which is required in selenoproteins such as glutathione peroxidases and thioredoxin reductases1,2. Here, we show that selenophosphate synthetase 2 (SEPHS2), an enzyme in the selenocysteine biosynthesis pathway, is essential for survival of cancer, but not normal, cells. "
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2. | Starvation
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3. | Osteoarthritis
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4. | Infections
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5. | Hypersensitivity (Allergy)
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