xylopine

RN given refers to (R)-isomer; RN for cpd without isomeric designation not available 3/90; structure given in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Damayanti, Yuvita Dian: 1 article (12/2019)
2.	Keller, Paul A: 1 article (12/2019)
3.	Nugraha, Ari Satia: 1 article (12/2019)
4.	Wangchuk, Phurpa: 1 article (12/2019)
5.	Bezerra, Daniel Pereira: 1 article (01/2017)
6.	Costa, Emmanoel Vilaça: 1 article (01/2017)
7.	Menezes, Leociley Rocha Alencar: 1 article (01/2017)
8.	Santos, Luciano de Souza: 1 article (01/2017)
9.	Silva, Valdenizia Rodrigues: 1 article (01/2017)
10.	Soares, Milena Botelho Pereira: 1 article (01/2017)

1.	Carcinoma (Carcinomatosis) 01/01/2017 - "In this study, the underlying mechanism of xylopine cytotoxicity was assessed in human colon carcinoma HCT116 cells. "
2.	Neoplasms (Cancer) 01/01/2017 - "Xylopine displayed potent cytotoxicity in different cancer cell lines in monolayer cultures and in a 3D model of cancer multicellular spheroids formed from HCT116 cells. " 01/01/2017 - "In conclusion, xylopine has potent cytotoxicity to different cancer cell lines and is able to induce oxidative stress and G2/M phase arrest, triggering caspase-mediated apoptosis by the p53-independent pathway in HCT116 cells." 12/03/2019 - "Other alkaloids such as (+)-Xylopine and isocoreximine indicated significant anti-cancer activity against A549 and K-562 cell lines, respectively. " 01/01/2017 - "Xylopine is an aporphine alkaloid that has cytotoxic activity to cancer cells. "