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1-hexyl-4-amino-2-methylquinolinium

structure given in first source; RN given refers to iodide

Also Known As:

1-HAQ; HAQ iodide

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolinium Compounds: 1
        1-hexyl-4-amino-2-methylquinolinium: 3

Experts

1.	Bello-Onaghise, God'spower: 1 article (03/2020)
2.	Chen, Xingru: 1 article (03/2020)
3.	Chen, Xueying: 1 article (03/2020)
4.	Cui, Wenqiang: 1 article (03/2020)
5.	Li, Xiubo: 1 article (03/2020)
6.	Li, Yanhua: 1 article (03/2020)
7.	Liu, Xin: 1 article (03/2020)
8.	Qu, Qianwei: 1 article (03/2020)
9.	Wang, Jinpeng: 1 article (03/2020)
10.	Xing, Xiaoxu: 1 article (03/2020)

Related Diseases

1.	Carcinogenesis 05/01/2000 - "In addition, 1-HAQ has a synergistic effect with methylazoxymethaol (MAM) acetate on colon carcinogenesis. " 04/01/1994 - "In addition, the synergistic effect of 1-HAQ with MAM acetate in colon carcinogenesis might be related to biological effects of the cytokines expressed in the inflammatory condition generated by 1-HAQ." 05/01/2000 - "Thus, these cytokines may act as growth factors in rat colon carcinogenesis by MAM acetate and 1-HAQ and the synergistic effect of 1-HAQ with MAM acetate might be related to the biological effects of the cytokines expressed in the inflammatory conditions induced by 1-HAQ." 04/01/1994 - "The results indicate that TNF-alpha and IL-1 alpha may act as growth factors in rat colon carcinogenesis by MAM acetate and 1-HAQ. "
2.	Neoplasms (Cancer) 05/01/2000 - "Long-term feeding of 1-HAQ induced hyper-cell proliferation in rat colonic crypts with ulcerative changes, crypt abscess, severe inflammation and erosion before the occurrence of tumors, which are similar to those found in human UC. "
3.	Bovine Mastitis 03/01/2020 - "Therefore, it can be inferred that 1-hAQ may serve as a potential source of organic compound for the development of novel alternative drugs in mitigating the menace of bovine mastitis."
4.	Inflammation (Inflammations) 05/01/2000 - "Long-term feeding of 1-HAQ induced hyper-cell proliferation in rat colonic crypts with ulcerative changes, crypt abscess, severe inflammation and erosion before the occurrence of tumors, which are similar to those found in human UC. "
5.	Colonic Neoplasms (Colon Cancer) 05/01/2000 - "The polymerase chain reaction-single strand conformation polymorphism analysis revealed no mutations in Ki-ras and p53 in colonic neoplasms induced by MAM acetate + 1-HAQ, MAM acetate alone or 1-HAQ alone. " 05/01/2000 - "Increased expression in TNF-alpha and IL-1alpha was found in these induced colonic neoplasms, and the expression was more remarkable in colonic mucosa of rats exposed to MAM acetate + 1-HAQ, MAM acetate or 1-HAQ when compared with that in untreated rats. "

Related Drugs and Biologics

1.	Intercellular Signaling Peptides and Proteins (Growth Factors)
2.	Cytokines
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4.	Acetates (Acetic Acid Esters)
5.	Interleukin-1alpha (Interleukin 1 alpha)