HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

5- iodo- N- ((1- ethyl- 2- pyrrolidinyl)methyl)- 2,3- dihydrobenzofurancarboxamide

dopamine receptor imaging agent; RN and structure given in first source

Also Known As:

125I-IBF; 5-iodo-7-N-((1-ethyl-2-pyrrolidinyl)methyl)carboxamido-2,3-dihydrobenzofuran; iodine-123-IBF

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - 5-iodo-N-((1-ethyl-2-pyrrolidinyl)methyl)-2,3-dihydrobenzofurancarboxamide: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - 5-iodo-N-((1-ethyl-2-pyrrolidinyl)methyl)-2,3-dihydrobenzofurancarboxamide: 1

Related Diseases

1.	Amelanotic Melanoma (Amelanotic Melanomas) 01/01/1996 - "The binding of 125I-IBF correlated with the amount of melanin present in the metastases; two amelanotic melanomas both failed to bind 125I-IBF. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1996 - "The binding of 125I-IBF correlated with the amount of melanin present in the metastases; two amelanotic melanomas both failed to bind 125I-IBF. " 01/01/1996 - "Findings were compared to the results of PET and metastasis histochemistry: D2 receptor mRNA assay (metastases: n = 5; melanoma cell lines: n = 4) using the reverse transcriptase polymerase chain reaction (RT-PCR) versus D2 receptor-transfected Chinese hamster ovary cell controls: in vitro 125I-IBF binding (n = 19), and immunohistochemical staining for dopamine D2 receptor protein (n = 19). "
3.	Melanoma (Melanoma, Malignant) 01/01/1996 - "Findings were compared to the results of PET and metastasis histochemistry: D2 receptor mRNA assay (metastases: n = 5; melanoma cell lines: n = 4) using the reverse transcriptase polymerase chain reaction (RT-PCR) versus D2 receptor-transfected Chinese hamster ovary cell controls: in vitro 125I-IBF binding (n = 19), and immunohistochemical staining for dopamine D2 receptor protein (n = 19). "

Related Drugs and Biologics

1.	Dopamine D2 Receptors (Dopamine D2 Receptor)
2.	Messenger RNA (mRNA)
3.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
4.	Proteins (Proteins, Gene)
5.	Melanins (Melanin)