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NAPAVIN
structure given in first source; photoreactive vinblastine derivative
Also Known As:
3-(((2-amino-(4-azido-2-nitrophenyl)ethyl)amino)carbonyl)-O(4)-deacetyl-3-de-(methoxycarbonyl)vincaleukoblastine
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vinblastine: 3373
NAPAVIN: 1
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vinblastine: 3373
NAPAVIN: 1
Indolizines: 3
Indolizidines: 2
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Vinca Alkaloids: 463
Vinblastine: 3373
NAPAVIN: 1
Related Diseases
1.
Carcinoma (Carcinomatosis)
01/15/1990 - "
We have synthesized a new photoreactive vinblastine derivative, 3-[[[2-amino(4-azido-2-nitrophenyl)ethyl]amino] carbonyl]-O4-deacetyl-3-de-(methoxycarbonyl)-vincaleukoblastine (NAPAVIN), which absorbs light at around 450 nm. We report here its effects in vitro on multidrug-resistant mouse HD33 Ehrlich-Lettré ascites cells, on Chinese hamster ovary CHRC5S3 cells, on the corresponding drug-sensitive cells, on chemosensitive rat TMA1 mammary carcinoma, and on human SW48 colon carcinoma cells.
"
2.
Ascites
01/15/1990 - "
Sensitization of multidrug-resistant mouse ascites HD33 and Chinese hamster ovary CHRC5S3 cells by a photoreactive vinblastine derivative, NAPAVIN.
"
01/15/1990 - "
We have synthesized a new photoreactive vinblastine derivative, 3-[[[2-amino(4-azido-2-nitrophenyl)ethyl]amino] carbonyl]-O4-deacetyl-3-de-(methoxycarbonyl)-vincaleukoblastine (NAPAVIN), which absorbs light at around 450 nm. We report here its effects in vitro on multidrug-resistant mouse HD33 Ehrlich-Lettré ascites cells, on Chinese hamster ovary CHRC5S3 cells, on the corresponding drug-sensitive cells, on chemosensitive rat TMA1 mammary carcinoma, and on human SW48 colon carcinoma cells.
"
Related Drugs and Biologics
1.
Vinblastine (Vinblastine Sulfate)