|1.||Yang, Li: 1 article (04/2014)|
|2.||Shah, Kaushik: 1 article (04/2014)|
|3.||Wangler, Naomi J: 1 article (04/2014)|
|4.||Abbruscato, Thomas J: 1 article (04/2014)|
|5.||Rashid, Mamoon: 1 article (04/2014)|
|6.||Arumugam, Thiruma V: 1 article (04/2014)|
|7.||Karamyan, Vardan T: 1 article (04/2014)|
|8.||Checler, Frédéric: 1 article (04/2014)|
|9.||Bell, Lauren N: 1 article (05/2010)|
|10.||Lee, Lydia: 1 article (05/2010)|
04/01/2014 - "This study also documents sustained functional up-regulation of neurolysin in frontoparietal cortical membranes for at least 7 days after stroke, which appears not to be transcriptionally or translationally regulated, but rather depends on translocation of cytosolic neurolysin to the membranes and mitochondria. "
04/01/2014 - "Experimental stroke: neurolysin back on stage."
04/01/2014 - "Functional up-regulation of endopeptidase neurolysin during post-acute and early recovery phases of experimental stroke in mouse brain."
04/01/2014 - "In this study, we provide evidence for the first time that membrane-bound endopeptidase neurolysin is up-regulated in different parts of mouse brain affected by focal ischemia-reperfusion in a middle cerebral artery occlusion model of stroke. "
04/01/2014 - "Considering diversity of endogenous neurolysin substrates (neurotensin, bradykinin, angiotensins I/II, substance P, hemopressin, dynorphin A(1-8), metorphamide, somatostatin) and the well-documented role of these peptidergic systems in pathogenesis of stroke, resistance to ischemic injury and/or post-stroke brain recovery, our findings suggest that neurolysin may play a role in processes modulating the brain's response to stroke and its recovery after stroke."
|2.||Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
07/01/2007 - "Metallopeptidase, neurolysin, as a novel molecular tool for analysis of properties of cancer-producing matrix metalloproteinases-2 and -9."
01/01/2007 - "Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth."
07/01/2007 - "The possible application of neurolysin displayed on the yeast cell surface, as a safe protein alternative to MMP-2 and MMP-9 which induce cancer cell growth, invasion, and metastasis, to analysis of properties of the MMPs, including the screening of inhibitors and analysis of inhibition mechanism etc., are also discussed."
01/01/2007 - "Thimet oligopeptidase (TOP) and neurolysin activities were then investigated in B16F10-Nex2 melanoma cells aiming at gene sequencing, enzyme distribution and activity, influence on tumor development, substrate specificity, hydrolytic products and susceptibility to inhibitors. "
07/01/2007 - "To compare the substrate preferences of rat brain neurolysin and cancer-producing matrix metalloproteinases (MMPs), which have the same architecture in their catalytic domains, the cleavage activity of neurolysin toward MMP-specific fluorescence-quenching peptides was quantitatively measured. "
|5.||Hypotension (Low Blood Pressure)
04/01/2008 - "In mice, mast cells can degrade NT and reduce NT-induced hypotension and CLP-associated mortality, and optimal expression of these effects requires mast cell expression of neurotensin receptor 1 and neurolysin. "
03/01/2005 - "Hemopressin causes hypotension in anesthetized rats and is metabolized in vivo and in vitro by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE). "
|2.||thimet oligopeptidase (endo-oligopeptidase)
|5.||Neurotensin Receptors (Neurotensin Receptor)
|6.||Extracellular Matrix Proteins
|8.||Somatostatin (Somatotropin Release-Inhibiting Factor)
|9.||Proteins (Proteins, Gene)