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glycyl-tyrosyl-lysine-DTPA

Also Known As:

GYK-DTPA; Gly-Tyr-Lys-DTPA

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Pentetic Acid: 1751
      - glycyl-tyrosyl-lysine-DTPA: 4
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Pentetic Acid: 1751
        glycyl-tyrosyl-lysine-DTPA: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - glycyl-tyrosyl-lysine-DTPA: 4

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 04/01/1992 - "These preliminary results demonstrate that In-111 B72.3 GYK-DTPA is a safe monoclonal antibody conjugate that has a high sensitivity for identifying primary colorectal cancer. " 04/01/1992 - "As part of an open-labeled nonrandomized multi-institutional Phase III study, the authors compared the results of In-111 (In-111) B72.3 glycyl-tyrosyl-n-diethylenetriaminepentaacetic acid lysine (GYK-DTPA) monoclonal antibody scintigraphy with computed tomography (CT), surgery, histopathology, immunohistology, and human antibody response in 23 patients with primary colorectal carcinoma. "
2.	Adenocarcinoma 07/01/1993 - "B72.3, a monoclonal antibody with reactivity against human adenocarcinomas, was coupled with linker-chelator GYK-DTPA using carbohydrate mediated conjugation chemistry and radiolabeled with yttrium-90. " 07/01/1993 - "B72.3, a monoclonal antibody with reactivity against human adenocarcinomas was obtained from the Cytogen Corporation in the form of an immunoconjugate coupled with linker-chelator GYK-DTPA by using proprietary carbohydrate directed site specific chemistry. "
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/01/1994 - "Uptake of In-111 GYK-DTPA B72.3 monoclonal antibody in metastatic squamous cell carcinoma."

Related Drugs and Biologics

1.	Monoclonal Antibodies
2.	B72.3 antibody
3.	Lysine (L-Lysine)
4.	Acids
5.	Chelating Agents
6.	Carbohydrates
7.	Immunoconjugates (Immunoconjugate)
8.	Yttrium-90