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octa-2,4,6-trienoic acid

Also Known As:

2,4,6-octatrienoic acid; LGD1550

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - octa-2,4,6-trienoic acid: 2

Experts

1.	Costa, Claudia: 1 article (12/2018)
2.	Fortuna, Maria C: 1 article (12/2018)
3.	Garelli, Valentina: 1 article (12/2018)
4.	Lombardi, Mara: 1 article (12/2018)
5.	Rossi, Alfredo: 1 article (12/2018)
6.	Sama, Elisa: 1 article (12/2018)
7.	Senis, Daniela: 1 article (12/2018)
8.	Grandis, Jennifer Rubin: 1 article (09/2003)
9.	Johnson, Daniel E: 1 article (09/2003)
10.	Lamph, William W: 1 article (09/2003)

Related Diseases

1.	Actinic Keratosis 12/01/2018 - "Preclinical published data on parrodiene-derivative 2,4,6-octatrienoic acid, encourages us to study and to evaluate the effect of a topical product containing it in patients affected by mild to moderate actinic keratosis. "
2.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/15/2003 - "Responsiveness to the retinoic acid receptor-selective retinoid LGD1550 correlates with abrogation of transforming growth factor alpha/epidermal growth factor receptor autocrine signaling in head and neck squamous carcinoma cells."
3.	Squamous Cell Carcinoma of Head and Neck 09/15/2003 - "In contrast, EGFR autocrine signaling pathways were not altered in HNSCC cells that were resistant to the growth inhibitory effects of LGD1550. " 09/15/2003 - "A series of HNSCC cell lines were characterized with respect to proliferation and apoptosis after LGD1550 treatment. " 09/15/2003 - "The present investigation was undertaken to determine the mechanism of responsiveness to an retinoic acid receptor-selective retinoid (LGD1550) that has shown antitumor efficacy in a xenograft model of HNSCC. "

Related Drugs and Biologics

1.	ErbB Receptors (EGF Receptor)
2.	Retinoic Acid Receptors (Retinoic Acid Receptor)
3.	Transforming Growth Factor alpha (TGF-alpha)
4.	Retinoids