AT 2433-B1

indolocarbazole from Actinomadura melliaura; iso-AT2433-B1 is a diastereoisomer; structure in first source

Also Known As:

AT2433-B1; iso-AT2433-B1

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Leukemia 11/01/2002 - "The two antibiotics AT2433-A1 and AT2433-B1 proved to be highly cytotoxic to leukemia cells and this may be a consequence of their tight intercalative binding to DNA, preferentially into GC-rich sequences as inferred from DNase I footprinting studies and surface plasmon resonance measurements. "

1.	DNA (Deoxyribonucleic Acid)
2.	Deoxyribonuclease I (Nickase)
3.	Anti-Bacterial Agents (Antibiotics)
4.	AT 2433-A1