|1.||Balasubramanian, Maruthaiveeran Periyasamy: 3 articles (09/2015 - 08/2012)|
|2.||Perumal, Srinivasan: 2 articles (10/2012 - 08/2012)|
|3.||Madankumar, Arumugam: 1 article (09/2015)|
|4.||Rengarajan, Thamaraiselvan: 1 article (09/2015)|
|5.||Sathishkumar, Venkatachalam: 1 article (09/2015)|
|6.||Nandakumar, Natarajan: 1 article (09/2015)|
|7.||Lokeshkumar, Booupathy: 1 article (09/2015)|
|8.||Suslov, Evgeniy V: 1 article (01/2015)|
|9.||Pykhtina, Maria B: 1 article (01/2015)|
|10.||Rogachev, Artem D: 1 article (01/2015)|
08/01/2013 - "The observed anticancer property of myrtenal may be due to the involvement and expression of p53 and influence in the mitochondrial and lysosomal membrane integrity and also interference in the gluconeogenesis process of cancer cells. "
01/01/2015 - "The most promising results were obtained for compound 2b which was synthesized from 1-aminoadamantane and (-)-myrtenal and revealed a high activity against all tumor lines used (CTD50 = 12 ÷ 21 µM) along with low toxicity with respect to MDCK cells (CTD50 = 1500 µM). "
09/01/2015 - "Treatment with myrtenal to cancer bearing animals resulted in a remarkable increase in the inherent antioxidants and excellent modulation in the morphological and physiological nature of the colon tissue. "
08/01/2013 - "Myrtenal is a novel class of compound belongs to monoterpenes found predominantly in mint, pepper, etc., and it was shown to have excellent pharmacological activities against many diseases among which cancer is imperative. "
08/01/2012 - "Treatment with myrtenal to cancer bearing animals resulted in remarkable increase in the inherent antioxidants and excellent modulation in the proteins of apoptotic and anti-apoptotic cascade. "
|2.||Body Weight (Weight, Body)
12/01/2014 - "Protection of body weight loss of diabetic rats by myrtenal was noted. "
09/01/2015 - "Myrtenal treatment was started with (230 mg/Kg/body weight) by intragastric administration, one week prior to DMH induction and continued till the experimental period of 30 weeks. "
12/01/2014 - "Oral administration of myrtenal at doses of 20, 40, and 80 mg/kg body weight to diabetic rats for 28 days resulted in a significant reduction (P < 0.05) in the levels of plasma glucose, glycosylated hemoglobin (HbA1c), and an increase in the levels of insulin and hemoglobin (Hb). "
|3.||Hepatocellular Carcinoma (Hepatoma)
10/01/2012 - "Thus, this study shows that myrtenal has the ability to suppress the hepatocellular carcinoma in rats."
10/01/2012 - "Myrtenal, a natural monoterpene, down-regulates TNF-α expression and suppresses carcinogen-induced hepatocellular carcinoma in rats."
08/01/2012 - "It is concluded that myrtenal exhibits excellent free radical scavenging activity and anticancer activity through the suppression of hepatocellular carcinoma in wistar rats. "
08/01/2012 - "Our results demonstrated that myrtenal exhibits strong antioxidant property in all the in vitro assays and the in vivo results revealed that the antioxidant status was significantly decreased in hepatoma bearing animals. "
10/01/2012 - "In the present study, it is shown that myrtenal, a natural monoterpene, which acts as an antineoplastic agent against diethylnitrosamine induced phenobarbital promoted experimental hepatocellular carcinoma. "
|4.||Liver Neoplasms (Liver Cancer)
08/01/2013 - "Our results suggest that myrtenal is very efficient and useful compound in the treatment of liver cancer in future. "
10/01/2012 - "Our findings also showed that myrtenal restrains the liver cancer by preventing the DEN-PB induced up-regulation of TNF-α protein expression by immunoblot. "
08/01/2013 - "The results revealed that myrtenal significantly ameliorated the altered enzymes of carbohydrate metabolism, lysosomal and mitochondrial enzymes, and interestingly the tumor suppressor protein p53 was found to be significantly accumulated in myrtenal-treated animals, which inevitably confirms that myrtenal has a prominent role in preventing the liver cancer during treatment. "
|5.||Colonic Neoplasms (Colon Cancer)
|3.||Glycosylated Hemoglobin A (Glycosylated Hemoglobin)
|10.||Caspase 3 (Caspase-3)