3- (2'- spiroadamantane)- 4- methoxy- 4- (3''- phosphoryloxy)phenyl- 1,2- dioxetane

06/01/1997 - "The results showed that PCR and Biotin-AMPPD hybridization not only ruled out the non-specific PCR amplification and increased the reliability for clinical specineus of leptospirosis but also raised the detecting sensibility (from 71.3% to 86.1%). "
06/01/1997 - "[Analysis on speciems of serum and urine in 66 cases of early leptospirosis by PCR and biotin-AMPPD hybridization]."
06/01/1997 - "We used polymerase chain reaction (PCR) and Biotin-AMPPD hybridization to detect leptospiral DNA in blood and urine samples in 66 patients at the early stage of leptospirosis. "
09/01/1992 - "We have detected and analysed the leptospiral DNA in serum of patients with early Leptospirosis from the epidemic area of China by PCR and DNA hybridization with Digoxigenin (Dig)-3-(2'-Spiroadamantane)-4-methoxy-4-(3"-phosphoryloxy)- phenyl-1,2-dioxetane (AMPPD) to develop a sensitive, specific and reliable technique for the early diagnosis of leptospirosis, and full satisfactory results have obtained. "
09/01/1992 - "[The detection and analysis of leptospiral DNA in patients' serum of early leptospirosis by polymerase chain reaction and DNA hybridization with digoxigenin-AMPPD]."

01/01/2021 - "Herein, we constructed a chemiluminescence theranostics platform named MSN@H6L@β-CD@AMPPD NPs for liver cancer-specific, in situ diagnosis and therapy without an external light source. "