|1.||Busch, Christian: 2 articles (08/2015 - 11/2012)|
|2.||Schott, Sarah: 2 articles (08/2015 - 11/2012)|
|3.||Tiwari, Sanjay: 1 article (08/2015)|
|4.||Vallet, Sonia: 1 article (08/2015)|
|5.||Noor, Seema: 1 article (08/2015)|
|6.||Schem, Christian: 1 article (08/2015)|
|7.||Tower, Robert J: 1 article (08/2015)|
|8.||Ikenberg, Kristian: 1 article (11/2012)|
|9.||Niessner, Heike: 1 article (11/2012)|
|10.||Venturelli, Sascha: 1 article (11/2012)|
08/01/2015 - "A cell line-specific, dose-related cytotoxicity was observed for 5-FdU-ale in all cancer cell lines tested, which was significantly less toxic than 5-FdU alone when compared to the benign osteoblasts or stromal cells. "
11/01/2010 - "Tetra-branched NT armed with 5-FdU was used for in vivo experiments in HT-29-xenografted mice and produced a 50% reduction in tumor growth with respect to animals treated with the free drug. "
09/15/2000 - "We analyzed the cytotoxic properties of the new heterodinucleoside phosphate dimer 5-FdU-NOAC, which is composed of the cytotoxic drugs 5-FdU and N(4)-octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC) against human prostate tumor cells. "
|2.||Melanoma (Melanoma, Malignant)
11/01/2012 - "We evaluated the cytotoxicity of these heterodinucleoside phosphate analogs, their corresponding monomers ECyd and 5-FdU and combinations thereof on six metastatic melanoma cell lines and six ex vivo patient-derived melanoma cells in comparison to current standard cytostatic agents and the BRAF V600E inhibitor Vemurafenib. "
01/01/1992 - "The total number of breaks showed a significant difference among individuals in both groups, however, the average frequencies of 5-FdU plus caffeine-induced, as well as spontaneous damages in PBL from melanoma patients, were higher than those from healthy volunteers. "
08/01/2015 - "In vitro cytotoxicity of ale, 5-FdU or 5-FdU-ale was measured with Alamar Blue and MUH cell viability assays in 14 malignant melanoma, multiple myeloma, bone marrow-derived stromal cell and osteoblast-like cell lines. "
11/01/2010 - "Cytotoxicity on human cell lines from colon (HT-29), pancreas (PANC-1) or prostate (PC-3) carcinoma indicated branched NT conjugated with MTX and 5-FdU as the most active agents on PANC-1 (EC(50) 4.4e-007 M) and HT-29 (1.1e-007 M), respectively. "
09/15/2000 - "5-FdU-NOAC effects on cell proliferation, cell cycle distribution, thymidylate synthase activity, and apoptosis were investigated in vitro in the two human prostate carcinoma cell lines DU-145 and PC-3 and compared to cells treated with the corresponding single drugs 5-FdU and NOAC. "
06/01/2006 - "To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides: 5-(dimethoxymethyl)-2'-deoxyuridine (2b), 5-(diethoxymethyl)-2'-deoxyuridine (3b), 5-formyl-2'-deoxyuridine ethylene acetal (4b), and 5-formyl-2'-deoxyuridine propylene acetal (5b). "
|5.||Caffeine (No Doz)
|7.||2'- deoxy- 5- fluorouridylyl- (5'- 5')- N(4)- octadecyl- 1- arabinofuranosylcytosine
|8.||N(4)- octadecyl- 1- arabinofuranosylcytosine