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protein kinase inhibitor peptide

18 amino acid residues given in first source; corresponds to the inhibitory domain of the heat-stable protein kinase inhibitor

Also Known As:

PKIP

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - protein kinase inhibitor peptide: 7

Experts

1.	Lai, Qingying: 2 articles (01/2020 - 01/2019)
2.	Wu, Wenbi: 2 articles (01/2020 - 01/2019)
3.	Xu, Lixia: 2 articles (01/2020 - 01/2019)
4.	Yang, Kai: 2 articles (01/2020 - 01/2019)
5.	Yuan, Meijin: 2 articles (01/2020 - 01/2019)
6.	Zhu, Leyuan: 2 articles (01/2020 - 01/2019)
7.	Chen, Xi: 1 article (03/2021)
8.	Qian, Wenwei: 1 article (03/2021)
9.	Wang, Yiou: 1 article (03/2021)
10.	Yin, Meihua: 1 article (03/2021)

Related Diseases

1.	Virus Diseases (Viral Diseases) 01/01/2020 - "In the present study, double-stranded RNA was used to silence pkip expression during virus infection, resulting in the significant reduction of occlusion body production and polyhedrin expression. " 01/01/2020 - "Since PKIP was reported to interact with and stimulate the activity of virus-encoded protein kinase PK1 and PK1 was involved in the hyperphosphorylation of viral basic protein P6.9, which was required for the maximal hyperexpression of very late genes, we sought to determine the association between PKIP and P6.9. Further experiments showed that PKIP interacted with P6.9 during virus infection, and the deletion of pkip resulted in decreased hyperphosphorylation of P6.9. Taken together, our results indicated that PKIP is involved in hyperphosphorylation of P6.9, which in return maybe required for hyperexpression of very late genes."
2.	Osteoarthritis 11/01/2018 - "Correlations between the PKIP and other measures (e.g., the American Knee Society score and the Knee Injury and Osteoarthritis Outcome Score) provided evidence of construct validity. " 03/01/2021 - "Of the 155 articles on 34 instruments included, nine PROMs met the minimum requirements for psychometric validation and can be recommended to use as measures of TKA outcome: Oxford Knee Score (OKS); OKS-Activity and Participation Questionnaire (OKS-APQ); 12-item short form Knee Injury and Osteoarthritis Outcome (KOOS-12); KOOS Physical function Short form (KOOS-PS); Western Ontario and McMaster Universities Arthritis Index-Total Knee Replacement function short form (WOMAC-TKR); Lower Extremity Functional Scale (LEFS); Forgotten Joint Score (FJS); Patient's Knee Implant Performance (PKIP); and University of California Los Angeles (UCLA) activity score. "
3.	Knee Injuries (Knee Injury) 11/01/2018 - "Correlations between the PKIP and other measures (e.g., the American Knee Society score and the Knee Injury and Osteoarthritis Outcome Score) provided evidence of construct validity. " 03/01/2021 - "Of the 155 articles on 34 instruments included, nine PROMs met the minimum requirements for psychometric validation and can be recommended to use as measures of TKA outcome: Oxford Knee Score (OKS); OKS-Activity and Participation Questionnaire (OKS-APQ); 12-item short form Knee Injury and Osteoarthritis Outcome (KOOS-12); KOOS Physical function Short form (KOOS-PS); Western Ontario and McMaster Universities Arthritis Index-Total Knee Replacement function short form (WOMAC-TKR); Lower Extremity Functional Scale (LEFS); Forgotten Joint Score (FJS); Patient's Knee Implant Performance (PKIP); and University of California Los Angeles (UCLA) activity score. "
4.	Infections 07/05/1998 - "The effect of PKIP on very late gene transcription may be a secondary effect of the block in the late phase of infection. " 01/01/2019 - "The pkip-encoded protein PKIP could be detected at late phase during infection and was distributed in both the cytoplasm and nuclei of viruses-infected cells, with a ring pattern near the inner nuclear membrane and punctate distribution in the virogenic stroma area. "
5.	Hepatocellular Carcinoma (Hepatoma) 09/01/2008 - "The inhibition of PKA with H89, cyclic AMP (cAMP) antagonists, or the protein kinase inhibitor peptide reduced HCV entry into Huh-7.5 hepatoma cells. "

Related Drugs and Biologics

1.	Double-Stranded RNA (RNA, Double Stranded)
2.	Proteins (Proteins, Gene)
3.	Protein Kinases (Protein Kinase)
4.	Cyclic AMP (AMP, Cyclic)
5.	N- (2- (4- bromocinnamylamino)ethyl)- 5- isoquinolinesulfonamide (h89)

Related Therapies and Procedures

1.	Knee Replacement Arthroplasty (Total Knee Replacement)