epiberberine

03/05/2016 - "Thus, epiberberine should be considered as one of the promising natural drugs for the treatment of dyslipidemia. "
03/05/2016 - "This study aimed to evaluate the cholesterol-lowering effect of epiberberine in dyslipidemia Syrian golden hamsters induced by high fat and high cholesterol (HFHC) diet and its regulation mechanism on some key genes involved in cholesterol metabolism. "
03/05/2016 - "Epiberberine reduces serum cholesterol in diet-induced dyslipidemia Syrian golden hamsters via network pathways involving cholesterol metabolism."
11/01/2020 - "All the available research studies indicated that epiberberine is a multi-target small molecule with a low toxicity and exerts many activities including anti-adipogenesis via Akt and ERK pathways, anti-dyslipidemia via inhibition on cholesterol synthesis, anti-cancer via p53/Bax apoptosis pathway, anti-bacterial, improvement in diabetes and Alzheimer's disease. "
11/01/2020 - "High-quality researches published in last two decades were retrieved from Web of science, ScienceDirect, PubMed and Springer with keywords namely 'epiberberine', 'protoberberine', 'coptis', 'huanglian', 'Coptidis rhizoma' and vital targets of some pathways in anti-adipogenesis, anti-dyslipidemia and anti-cancer activities. "

09/14/2023 - "Epiberberine is a potent antitumour agent for several types of cancer. "
05/17/2020 - "Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice."
11/01/2020 - "All the available research studies indicated that epiberberine is a multi-target small molecule with a low toxicity and exerts many activities including anti-adipogenesis via Akt and ERK pathways, anti-dyslipidemia via inhibition on cholesterol synthesis, anti-cancer via p53/Bax apoptosis pathway, anti-bacterial, improvement in diabetes and Alzheimer's disease. "
11/01/2020 - "High-quality researches published in last two decades were retrieved from Web of science, ScienceDirect, PubMed and Springer with keywords namely 'epiberberine', 'protoberberine', 'coptis', 'huanglian', 'Coptidis rhizoma' and vital targets of some pathways in anti-adipogenesis, anti-dyslipidemia and anti-cancer activities. "

11/01/2020 - "All the available research studies indicated that epiberberine is a multi-target small molecule with a low toxicity and exerts many activities including anti-adipogenesis via Akt and ERK pathways, anti-dyslipidemia via inhibition on cholesterol synthesis, anti-cancer via p53/Bax apoptosis pathway, anti-bacterial, improvement in diabetes and Alzheimer's disease. "

09/14/2023 - "This study is aimed at investigating the regulatory and molecular mechanism of epiberberine on HNSSC cell metastasis. "
09/14/2023 - "Epiberberine suppresses the metastasis of head and neck squamous cell carcinoma cells by regulating the MMP-13 and JNK pathway."
08/01/2022 - "By decreasing β-catenin expression, increasing GSK-3β expression and decreasing N-cadherin expression, increasing E-cadherin expression, which proved that epiberberine, berberrubine and dihydroberberine inhibited of metastasis of breast cancer cells through Wnt signaling pathway and reversed EMT except berberine. "

01/01/2023 - "Epiberberine (EPI), extracted from Rhizome Coptidis, has been shown to attenuate hyperlipidemia in vivo. "
01/01/2016 - "The present study is focused on the assessment of the antihyperglycemia and antidiabetic hyperlipidemia effect of five protoberberine alkaloids, berberine (BBR), coptisine (COP), palmatine (PAL), epiberberine (EPI), and jatrorrhizine (JAT), separated from R. "