CI 943

structure given in first source

Also Known As:

1H-Imidazo(1,2-c)pyrazolo(3,4-e)pyrimidine, 8-ethyl-7,8-dihydro-1,3,5-trimethyl-; 8-ethyl-7,8-dihydro-1,3,5-trimethyl-1H-imidazo(1,2-c)pyrazolo(3,4-e)pyrimidine; CI-943

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - CI 943: 2
  - Pyrimidines: 510
    - CI 943: 2

Related Diseases

1.	Shock 10/01/1989 - "CI-943 displays an antipsychotic-like profile in conditioned avoidance tests, inhibiting one-way avoidance in rats at doses that do not impair escape and inhibiting continuous avoidance in rats and squirrel monkeys at doses that do not impair shock termination responding. "
2.	Dystonia (Limb Dystonia) 01/01/1995 - "CI-943 does not cause dystonia in monkeys, a predictive symptom of extrapyramidal side effects (EPS). "
3.	Ataxia (Dyssynergia) 10/01/1989 - "Like available antipsychotics, CI-943 reduces spontaneous locomotion in mice and rats and inhibits compulsive cage climbing induced by apomorphine in mice at doses that do not produce ataxia. "
4.	Tardive Dyskinesia 10/01/1989 - "Unlike dopamine antagonists that produce tardive dyskinesia, CI-943 administered repeatedly at high doses does not produce behavioral supersensitivity to dopamine agonists in rats. "

Related Drugs and Biologics

1.	Dopamine Antagonists
2.	Dopamine Agonists (Dopamine Agonist)
3.	Antipsychotic Agents (Antipsychotics)
4.	Apomorphine