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alanylhistidine (Ala-His)

RN refers to all (L)-isomer

Also Known As:

Ala-His; alanylhistidine, (D-His-L-ALA)-isomer

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - alanylhistidine: 3

Related Diseases

1.	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/01/1993 - "We examined the profile of two bombesin (BN) antagonists, (CH3)2CHCO-His-Trp-Ala-Val-D-Ala-His-Leu-NHCH3] (ICI 216140) and [D-Phe6,des-Met14]BN(6-14)ethylamide (DPDM-BN EA), against neuromedin B-induced Ca2+ mobilization in the small cell lung cancer (SCLC) line NCI-H345. "
2.	Neoplasms (Cancer) 12/15/1999 - "Endostatin, a potent inhibitor of angiogenesis and tumor growth, is a COOH-terminal fragment of collagen XVIII derived through cleavage of an Ala-His linkage by an as yet unidentified endostatin-processing enzyme. "
3.	Edema (Dropsy) 12/01/1993 - "Ovine CRF(21-41), -Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys- Leu-Asp-Ile-Ala-NH2, its carboxy terminal carboxyl derivative, oCRF(21-41)-OH, and the fragments, oCRF(26-41) and oCRF(30-41), were inactive when assayed at 5 mg/kg i.v. on edema induced in the pentobarbital-anesthetized rat's hindpaw after immersion in 58 degrees C water for 1 min. Crude peptides, D-Leu-Ala-Thr-D-Tyr-Arg-Lys-Leu-Leu-Glu-Ile-D-Leu-NH2 and D-Ala-His-Ser-D-Asn-Arg-Lys-Leu-Leu-Glu-Ile-D-Leu-NH2, were found to have activity in this bioassay. "

Related Drugs and Biologics

1.	Collagen Type XVIII (Type XVIII Collagen)
2.	Endostatins
3.	Peptides (Polypeptides)
4.	Pentobarbital (Nembutal)
5.	Enzymes
6.	Bombesin
7.	leucyl-alanine
8.	arginyllysine
9.	Phe(6)-des-Met(14)- bombesin (6-14)-ethylamide
10.	ICI 216140