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1,3-diethyl-1-nitrosourea

structure given in first source

Also Known As:

N,N'-diethyl-N-nitrosourea; N-nitroso-N,N'-diethylurea; nitrosodiethylurea

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Nitrosourea Compounds: 21
      - Ethylnitrosourea: 850
        1,3-diethyl-1-nitrosourea: 3
- Nitroso Compounds: 446
  - Nitrosourea Compounds: 21
    - Ethylnitrosourea: 850
      - 1,3-diethyl-1-nitrosourea: 3

Related Diseases

1.	Neoplasms (Cancer) 01/01/1988 - "Although nitrosomethylurea did not induce colon tumors under these conditions, nitrosoethylurea did, together with nitrosodiethylurea and other nitrosoethylalkylureas. " 01/01/1989 - "Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas. " 01/30/1998 - "To investigate the two activities, brief treatments of male F344 rats with each of three mutagens, nitrosodimethylurea, nitrosodiethylurea and nitrosobis-(2-oxopropyl)-amine, were followed by chronic treatment (40 weeks) with one of four non-mutagens, nitrosomethyl-3-carboxypropylamine, nitrosodiethanolamine, nitrosomethyl-2-hydroxypropylamine or phenobarbital, the last being a well-known promotor of liver tumors in rats. "
2.	Nervous System Neoplasms (Neoplasms, Nervous System) 01/01/1989 - "Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas. "
3.	Mesothelioma 01/01/1989 - "Nitrosodimethylurea and nitroso-1-methyl-3-ethylurea gave rise primarily to tumors of the nervous system, whereas nitrosodiethylurea and nitroso-1-ethyl-3-methylurea gave rise to tumors of the mammary gland, lung, intestinal tract, nervous system, and testicular mesotheliomas. "

Related Drugs and Biologics

1.	N,N'-dimethylnitrosourea
2.	Phenobarbital (Luminal)
3.	Mutagens
4.	Methylnitrosourea (N-Methyl-N-nitrosourea)
5.	Ethylnitrosourea (N-Ethyl-N-nitrosourea)
6.	4-(N-nitroso-N-methylamino)butyric acid