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2-vanillin

Also Known As:

2-hydroxy-3-methoxybenzaldehyde; o-vanilin; o-vanillin

Networked: 15 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - Benzaldehydes: 9
    - 2-vanillin: 15

Experts

1.	Dang, Chunyan: 2 articles (11/2021 - 01/2021)
2.	Li, Hongling: 2 articles (11/2021 - 01/2021)
3.	Ma, Shuping: 2 articles (11/2021 - 01/2021)
4.	Meng, Yuna: 2 articles (11/2021 - 01/2021)
5.	Xue, Li: 2 articles (11/2021 - 01/2021)
6.	Cherif, Hosni: 2 articles (01/2021 - 03/2019)
7.	Haglund, Lisbet: 2 articles (01/2021 - 03/2019)
8.	Jarzem, Peter: 2 articles (01/2021 - 03/2019)
9.	Ouellet, Jean A: 2 articles (01/2021 - 03/2019)
10.	Gibson, J S: 2 articles (06/2014 - 03/2013)

Related Diseases

1.	Inflammation (Inflammations) 04/28/2015 - "Mice treated with o-vanillin exhibited reduced TLR2-induced inflammation. " 03/29/2019 - "Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. "
2.	Back Pain (Backache) 01/01/2021 - "Treatment with o-vanillin reduced the number of senescent cells, and increased matrix synthesis in IVD cells from back pain patients. " 01/01/2021 - "The reduction in senescence, SASP, and TLR-2 expression suggest o-vanillin as a potential disease-modifying drug for patients with disc degeneration and back pain." 01/01/2021 - "Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin." 03/29/2019 - "Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. "
3.	Neoplasms (Cancer) 04/22/2020 - "O-Vanillin Attenuates the TLR2 Mediated Tumor-Promoting Phenotype of Microglia." 01/01/2020 - "The results showed that the anti-cancer activity was barely reduced after modifying the surface of the Fe3O4/SiO2/APTS nanoparticles with 2-hydroxy-3-methoxybenzaldehyde as Schiff base and then Cu(II) complex. " 11/01/2021 - "In the present study, VALD-3, an important Schiff base ligand from o-vanillin derivatives was evaluated for its anti-cancer activity in vitro and in vivo against colorectal cancer. "
4.	Colorectal Neoplasms (Colorectal Cancer) 11/01/2021 - "In the present study, VALD-3, an important Schiff base ligand from o-vanillin derivatives was evaluated for its anti-cancer activity in vitro and in vivo against colorectal cancer. "
5.	Pain (Aches) 01/01/2023 - "This study aimed to determine if combining the two senolytic drugs, o-Vanillin and RG-7112, could more efficiently remove senescent cells and reduce the release of inflammatory factors and pain mediators in cells from degenerating human IVDs than either drug alone. "

Related Drugs and Biologics

1.	Curcumin
2.	Schiff Bases (Schiff Base)
3.	Ligands
4.	VALD-3
5.	vanillin
6.	Aldehydes
7.	Toll-Like Receptor 2
8.	Catenins
9.	Matrix Metalloproteinases (MMPs)
10.	Mitomycin (Mitomycin-C)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)