hemagglutinin esterase

a sialate-O-acetylesterase; virus glycoprotein antigenic determinant;

Also Known As:

HE protein, Coronavirus; HEF esterase, Influenza C virus; HEF glycoprotein, Influenza C virus; HEF protein, Influenza C virus; haemagglutinin-esterase-fusion protein, Influenza C virus

Networked: 42 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zandi, Milad: 6 articles (03/2022 - 01/2021)
2.	Soltani, Saber: 4 articles (12/2021 - 01/2021)
3.	Li, Feng: 2 articles (12/2021 - 01/2018)
4.	Wang, Dan: 2 articles (12/2021 - 01/2018)
5.	Frost, Petter: 2 articles (02/2014 - 01/2013)
6.	Hodneland, Kjartan: 2 articles (02/2014 - 01/2013)
7.	Rimstad, Espen: 2 articles (02/2014 - 01/2013)
8.	Wolf, Astrid: 2 articles (02/2014 - 01/2013)
9.	Abdulai, Suliat I: 1 article (10/2022)
10.	Adewole, Kayode E: 1 article (10/2022)

Related Diseases

1.	COVID-19 01/01/2022 - "Reply to letter entitled 'Diagnosis of COVID-19: hemagglutinin-esterase gene is used for molecular assays?'" 01/01/2022 - "Diagnosis of COVID-19: hemagglutinin-esterase gene is used for molecular assays?" 08/01/2021 - "Hemagglutinin-esterase cannot be considered as a candidate for designing drug against COVID-19." 01/01/2020 - "We aimed to determine whether Arbidol, the hemagglutinin esterase inhibitor used in the treatment of COVID-19, was effective against SARS Cov-2 in silico. " 03/15/2022 - "In a published review entitled "COVID-19 diagnosis -A review of current methods", the authors considered hemagglutinin esterase as one of the structural proteins of SARS-CoV-2 and also they did not represent ORF3b, ORF9b, and ORF9c in SARS-CoV-2 genome structure. "
2.	Dysentery 01/01/2001 - "In this study, we attempted to define differences in the hemagglutinin-esterase (HE) glycoprotein between 11 bovine coronaviruses (BCV) recent (post-1991) and past (pre-1991) isolates from neonatal calf diarrhoea (NCD) and winter dysentery (WD) syndromes as a basis for strain differentiation related to the clinical source of the isolates. " 01/01/1997 - "Seven hybridoma cell lines producing monoclonal antibodies (MAbs) to the hemagglutinin-esterase (HE) glycoprotein of bovine coronavirus (BCV) were obtained from BALB/c mice that were immunized with an enriched peplomeric fraction of the winter dysentery (WD)-associated strain BCQ.2590. " 01/01/1997 - "Characterization of monoclonal antibodies to the hemagglutinin-esterase glycoprotein of a bovine coronavirus associated with winter dysentery and cross-reactivity to field isolates." 01/01/2013 - "Given that BCoV is better studied than equine coronaviruses and given the possibility of interspecies transmission of these viruses, this research was designed to compare the partial sequences of the spike glycoprotein (S), hemagglutinin-esterase protein (HE), and nucleoprotein (N) genes from coronaviruses from adult cattle with winter dysentery, calves with neonatal diarrhea, and horses. "
3.	Human Influenza (Influenza) 01/01/2019 - "During erythrocyte development, TER-119+ Ery-A and Ery-B cells could be stained by catalytically inactive bovine coronavirus hemagglutinin-esterase but not by the inactive influenza C hemagglutinin-esterase, while TER-119+ Ery-C cells and mature erythrocytes were recognized by both virolectins. " 11/26/2016 - "Analyses of Evolutionary Characteristics of the Hemagglutinin-Esterase Gene of Influenza C Virus during a Period of 68 Years Reveals Evolutionary Patterns Different from Influenza A and B Viruses." 10/01/1997 - "The phylogenetic tree constructed with the nucleotide sequences of the hemagglutinin-esterase (HE) genes of 25 influenza C strains isolated during the period from 1964 to 1988 revealed the existence of four discrete lineages. " 08/01/2010 - "Similarity to bovine and porcine torovirus hemagglutinin-esterase (BToV HE, PToV HE), bovine coronavirus HE (BCoV HE) and influenza C hemagglutinin-esterase-fusion (InfC HEF) proteins were exploited in a computational homology-based structure analysis of ISAV HE. " 03/01/2008 - "These ionizable residues are likely the structural basis for the pH dependence and sensitivity to ionic strength of influenza HA and hemagglutinin-esterase fusion proteins."
4.	Infections 12/01/2020 - "The hemagglutinin-esterase (HE) protein of betacoronavirus lineage A is a secondary receptor in the infection process and is involved in the emergence of new betacoronavirus genotypes with altered host specificity and tissue tropism. " 02/01/1995 - "Interaction of mouse hepatitis virus (MHV) spike glycoprotein with receptor glycoprotein MHVR is required for infection with an MHV strain that expresses the hemagglutinin-esterase glycoprotein." 06/01/2004 - "C infection and analyzed for antigenic characteristics with a set of monoclonal antibodies against hemagglutinin-esterase glycoproteins. " 01/01/2018 - "A DNA Vaccine Expressing Consensus Hemagglutinin-Esterase Fusion Protein Protected Guinea Pigs from Infection by Two Lineages of Influenza D Virus." 04/01/2016 - "The identified antiviral peptide efficiently impairs ISAV infection in vitro by specifically blocking hemagglutinin-esterase, a pivotal surface protein of this virus. "
5.	Neurologic Manifestations (Neurological Manifestations) 01/01/2021 - "Response to the letter, entitled "Role of hemagglutinin esterase protein in neurological manifestation of COVID-19"." 01/01/2021 - "Role of hemagglutinin esterase protein in neurological manifestation of COVID-19."

Related Drugs and Biologics

1.	umifenovir
2.	Glycoproteins (Glycoprotein)
3.	Proteins (Proteins, Gene)
4.	Monoclonal Antibodies
5.	Hemagglutinins (Hemagglutinin)
6.	Vaccines
7.	Neuraminidase (Sialidase)
8.	N-Acetylneuraminic Acid (Sialic Acid)
9.	Membrane Proteins (Integral Membrane Proteins)
10.	Neutralizing Antibodies

Related Therapies and Procedures

1.	Therapeutics