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ST 638

Also Known As:

ST-638; alpha-cyano-3-ethoxy-4-hydroxy-5-phenylmethylcinnamamide

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cinnamates: 48
      - ST 638: 2
- Sulfur Compounds: 278
  - Sulfides: 1062
    - ST 638: 2
Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Sulfides: 1062
        ST 638: 2
- Sulfur Compounds: 278
  - Hydrogen Sulfide: 2764
    - Sulfides: 1062
      - ST 638: 2

Related Diseases

1.	Lung Injury 01/01/1994 - "These studies strongly indicate that tyrosine kinase plays an important role in immune complex-triggered neutrophil-related lung disorders, and the novel tyrosine kinase inhibitor ST-638 attenuates lung injury by preventing superoxide production and neutrophil migration."
2.	Neoplasms (Cancer) 01/01/1991 - "Phosphorylation of Glu,Tyr4:1 in tumors (cytosolic fraction) was reduced to 77.8 +/- 8.7% of the control value by 10 microM ST 638 (p less than 0.05), and to 50.7 +/- 10.4% by 100 microM quercetin (p less than 0.01). "

Related Drugs and Biologics

1.	Superoxides (Superoxide)
2.	Protein-Tyrosine Kinases (Tyrosine Kinase)
3.	Antigen-Antibody Complex (Immune Complex)
4.	Tyrosine Kinase Inhibitors
5.	Quercetin