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pisiferic acid
from Chamaecyparis pisifera; RN given refers to 4aR-trans parent cpd
Also Known As:
pisiferic acid, (4aR-trans)-sodium salt
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Diterpenes: 1470
pisiferic acid: 1
Experts
1.
Aburai, N
: 1 article (08/2010)
2.
Kimura, K
: 1 article (08/2010)
3.
Ohnishi, M
: 1 article (08/2010)
4.
Yoshida, M
: 1 article (08/2010)
Related Diseases
1.
Leukemia
08/01/2010 - "
In vivo, the cytotoxicity of pisiferdiol toward human promyelocytic leukemia cell line HL60 with an IC(50) value of 18.3 microM was 2-fold and 7-fold stronger than those of pisiferic acid and oleic acid, and pisiferdiol induced apoptosis through a caspase 3/7-dependent mechanism involving the dephosphorylation of Bad(1), which is a PP2C substrate.
"
Related Drugs and Biologics
1.
Caspase 3 (Caspase-3)
2.
Oleic Acid (Oleate)