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2- succinyl- 6- hydroxy- 2,4- cyclohexadiene- 1- carboxylate synthase

E coli enzyme; catalyzes a menaqunone biosynthetic step, the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate from 2-ketoglutarate & isochorismate; requires thiamine pyrophosphate & liberates pyruvate from the isochorismate molecule; see also o-succinylbenzoate synthase
Also Known As:
E. coli succinyl CoA synthase; MenH protein, E coli; SHCHC synthase; YfbB protein, E coli
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