|1.||Schneider, Michael D: 2 articles (01/2004 - 03/2003)|
|2.||Sano, Motoaki: 2 articles (01/2004 - 03/2003)|
|3.||Yan, Christopher: 1 article (09/2015)|
|4.||Greenleaf, Arno L: 1 article (09/2015)|
|5.||Bartkowiak, Bartlomiej: 1 article (09/2015)|
|6.||Mohaghegh, Nima: 1 article (12/2011)|
|7.||Garrett, Alexander S: 1 article (12/2011)|
|8.||Seidel, Christopher: 1 article (12/2011)|
|9.||Washburn, Michael P: 1 article (12/2011)|
|10.||Swanson, Selene K: 1 article (12/2011)|
09/24/1999 - "Heat shock also induces Ser(2) phosphorylation, but we show here that this change in CTD modification and an accompanying induction of heat shock gene expression is independent of CTDK-I. The observation that SSA3/SSA4 expression is increased in ctk1Delta cells grown at normal temperature suggests a possible role for CTDK-I in transcription repression. "
10/01/1995 - "The weak CTD kinase activation occurring upon mild heat shock might be insufficient to compensate for the heat inactivation of the already existing CTD kinases. "
10/05/1990 - "Heat-shock and arsenite stress were found to stimulate strongly CTD kinase activity. "
06/02/1995 - "We have previously shown that in HeLa cells a protein kinase (HS-CTD kinase) activity is induced rapidly after a heat or sodium arsenite shock. "
08/11/1999 - "In the transcription process, TFIIE regulates TFIIH kinase activity that phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD and the CTD kinase Kin28, a subunit of TFIIH, have been shown to be dispensable for activation of several heat shock genes and the copper metallothionein gene CUP1. "
02/05/1991 - "We demonstrate here that the mouse CTD expressed in and purified from Escherichia coli can be phosphorylated in vitro by a p34cdc2/CDC28-containing CTD kinase from mouse ascites tumor cells. "
09/01/2015 - "The RNA Polymerase II C-terminal domain (CTD) kinase CDK12 has been implicated as a tumor suppressor and regulator of DNA damage response genes. "
|3.||Cardiomegaly (Heart Hypertrophy)
01/01/2004 - "Investigations of the CTD kinase module in cardiac hypertrophy provide a tentative initial map of a molecular circuit controlling cell size through regulated phosphorylation of RNAPII."
03/01/2003 - "A subset of cyclin-dependent protein kinases--Cdk7, Cdk8, and Cdk9--participates directly, in complex ways, with the fundamental machinery for gene transcription, as elements of general transcription factors whose substrate is the C-terminal domain (CTD) of RNA polymerase II. Here, we review recent data implicating the CTD kinase Cdk9 as a critical determinant of cardiac hypertrophy, in vitro and in vivo. "
|1.||RNA Polymerase II (RNA Polymerase B)
|3.||DNA Polymerase II
|4.||Positive Transcriptional Elongation Factor B
|5.||General Transcription Factors
|7.||Staphylococcal Protein A (A, Protein)
|9.||transcription factor TFIIE (TFIIE)