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Sch 434
drug combination containing loratadine & pseudoephedrine
Also Known As:
Sch-434
Networked:
3
relevant articles (
2
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Pharmaceutical Preparations
Drug Combinations: 5337
Sch 434: 3
Organic Chemicals: 133
Amines: 4871
Amino Alcohols: 20
Propanolamines: 4
Pseudoephedrine: 407
Sch 434: 3
Ethylamines: 5
Phenethylamines: 28
Pseudoephedrine: 407
Sch 434: 3
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Benzocycloheptenes
Dibenzocycloheptenes
Cyproheptadine: 709
Loratadine: 463
Sch 434: 3
Alcohols: 595
Amino Alcohols: 20
Propanolamines: 4
Pseudoephedrine: 407
Sch 434: 3
Propanols: 3
Propanolamines: 4
Pseudoephedrine: 407
Sch 434: 3
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Piperidines: 17
Cyproheptadine: 709
Loratadine: 463
Sch 434: 3
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Benzocycloheptenes
Dibenzocycloheptenes
Cyproheptadine: 709
Loratadine: 463
Sch 434: 3
Related Diseases
1.
Seasonal Allergic Rhinitis (Hay Fever)
08/01/1995 - "
The results of the study demonstrate that SCH 434 QD is more effective than placebo or either of its components alone in the treatment of seasonal allergic rhinitis.
"
06/01/1989 - "
We conclude that SCH 434 is a safe and effective treatment for symptoms of seasonal allergic rhinitis.
"
08/01/1995 - "
SCH 434 QD was consistently superior to placebo in controlling the symptoms of seasonal allergic rhinitis.
"
01/01/1994 - "
Comparative study of SCH 434 and CTM-D in the treatment of seasonal allergic rhinitis.
"
06/01/1989 - "
SCH 434: a new antihistamine/decongestant for seasonal allergic rhinitis.
"
2.
Sleep Initiation and Maintenance Disorders (Insomnia)
06/01/1989 - "
All treatments were safe and well tolerated, although insomnia and dry mouth were noted in a significant number of patients who received either SCH 434 or pseudoephedrine.
"
08/01/1995 - "
Insomnia and nervousness, adverse events commonly associated with pseudoephedrine, were noted in a significantly greater number of patients treated with SCH 434 QD or pseudoephedrine (p < or = 0.04) as compared with those treated with loratadine or placebo.
"
3.
Fatigue
01/01/1994 - "
A smaller proportion of patients in the SCH 434 group reported side effects, especially dry mouth (7% vs 19%, P = 0.07), fatigue (6% vs 25%, P < 0.01), and sedation (7% vs 22%, P < 0.03).
"
Related Drugs and Biologics
1.
Pseudoephedrine
2.
Loratadine (Alavert)
3.
Sulfates (Sulfates, Inorganic)
4.
Nasal Decongestants (Decongestants)
5.
Tablets
6.
Histamine Antagonists (Antihistamines)
7.
Chlorpheniramine (Chlorphenamine)