caffeoyl-CoA O-methyltransferase

catalyzes the methylation of caffeoyl-CoA to form trans-feruloyl-CoA; also accepts with low affinity various other caffeic esters as substrates; do not confuse with EC 2.1.1.68 which acts on caffeic acid; has been sequenced; GenBank L22203 (Stellaria longipes)

Also Known As:

CCoAMT; CCoAOMT; S-adenosyl-L-methionine-trans-caffeoyl-coenzyme A 3-O-methyltransferase; S-adenosylmethionin-trans-caffeoyl-coenzyme A 3-O-methyltransferase; S-adenosylmethionine-trans-caffeoyl-CoA 3-O-methyltransferase; SAM-C-CoA 3-O-methyltransferase; SAM-CCA-methyltransferase; caffeoyl-CoA-3-O-methyltransferase

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Methyltransferases: 5778
        caffeoyl-CoA O-methyltransferase: 8

Experts

1.	Li, Chuanshun: 1 article (01/2021)
2.	Qi, Yuting: 1 article (01/2021)
3.	Wang, Xingjun: 1 article (01/2021)
4.	Zhang, Quan: 1 article (01/2021)
5.	Zhao, Chuanzhi: 1 article (01/2021)
6.	Dixon, Richard A: 1 article (01/2018)
7.	Gallego-Giraldo, Lina: 1 article (01/2018)
8.	Gill, Upinder S: 1 article (01/2018)
9.	Ishiga, Yasuhiro: 1 article (01/2018)
10.	Mysore, Kirankumar S: 1 article (01/2018)

Related Diseases

1.	Mycoses (Diseases, Fungus) 08/01/2023 - "Furthermore, this study indicated that suppression of AsCCoAOMT resulted in marked root susceptibility to pathogenic fungal disease, implying a significant additional role of CCoAOMT in protecting plant vegetative parts from diseases. " 01/01/2018 - "We tested transgenic alfalfa plants downregulated for Caffeoyl-CoA O-methyltransferase (CCoAOMT) against an economically important fungal disease of alfalfa, Fusarium wilt caused by Fusarium oxysporum f. "
2.	Disease Resistance 01/01/2018 - "These results suggested that the increased accumulation and/or shift/spillover of flux towards the (iso)flavonoid pathway in CCoAOMT downregulated plants is associated with induced disease resistance." 11/01/1997 - "The data imply for the first time (to our knowledge) that the expression of phenyl-propanoid genes in grapevine is induced by SAR activators without phenotypic consequences and suggest a role for CCoAOMT and stilbene synthase in the disease-resistance response leading beyond the level of pathogenesis-related proteins as markers of the SAR."
3.	Dehydration (Water Stress) 08/01/2023 - "The expression analysis of genes revealed that drought-tolerant varieties showed enhanced mechanical support for water conduction by up-regulation of genes, Phenylalanine ammonia-lyase1 (PAL1), cinnamate-4-hydroxylase (C4H), 4-coumarate-CoA ligase (4CL), cinnamoyl-CoA reductase (CCR), caffeoyl-CoA O-methyltransferase (CCOMT), and cinnamyl-alcohol dehydrogenase (CAD6) in water stress conditions. " 01/01/2002 - "These proteins fell into two categories: (i) stress-related proteins, known to be induced by rapid water stress via abscisic acid (ABA)-dependent or -independent pathways [late embryogenesis abundant (LEA)-like and heat shock cognate (HS) 70, respectively], or in response to pathogens or oxidative stress [β-1,3 glucanase (BG), annexin] and (ii) metabolic enzymes [glutamine synthetase (GS), fructokinase (Frk), caffeoyl-CoA-3-O-methyltransferase (CCoAOMT)]. "
4.	Shock 01/01/2021 - "Notably, the transcript abundance of a large number of lignin biosynthesis genes such as CCoAOMT, C4H, CCR, CAD, POD, and C3'H in leaves was markedly elevated by salt shock. "
5.	Infections 02/01/1998 - "Two members of the CCoAOMT gene family appeared to be constitutively expressed in various plant organs and tissues whereas the two others were preferentially expressed in flower organs, after tobacco mosaic virus (TMV) infection or elicitor treatment of leaves. "

Related Drugs and Biologics

1.	caffeoyl-CoA O-methyltransferase
2.	Proteins (Proteins, Gene)
3.	Laccase
4.	Annexins
5.	Uridine Diphosphate Glucose Dehydrogenase
6.	Tubulin
7.	Salts
8.	Phenylalanine (L-Phenylalanine)
9.	Lignin
10.	Glutamate-Ammonia Ligase (Glutamine Synthetase)