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1-ethoxymethyl-5-fluorouracil
Also Known As:
EM-FU
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidinones: 71
Uracil: 1493
Fluorouracil: 26711
1-ethoxymethyl-5-fluorouracil: 3
Related Diseases
1.
Yoshida Sarcoma
02/01/1989 - "
After oral administration of BOF-A2 at 15 mg/kg to Yoshida sarcoma-bearing rats, BOF-A2 was hydrolyzed to EM-FU, CNDP and 5-FU, and their maximum concentrations in the blood were 2000 ng/ml, 300 ng/ml and 40 ng/ml, respectively.
"
12/01/1993 - "
Coadministration of CNDP with 1-ethoxymethyl-5-fluorouracil (EM-FU) to rats with Yoshida sarcoma elevated the level of 5-FU in both the blood and the tumor and enhanced the antitumor effect of EM-FU.
"
2.
Neoplasms (Cancer)
05/01/1990 - "
When BOF-A2 was given orally, blood levels of the main metabolites, EM-FU and CNDP, were maintained for a longer time in the tumor-bearing rats, and eventually the blood 5-FU levels were maintained over 12 hours.
"
12/01/1993 - "
Coadministration of CNDP with 1-ethoxymethyl-5-fluorouracil (EM-FU) to rats with Yoshida sarcoma elevated the level of 5-FU in both the blood and the tumor and enhanced the antitumor effect of EM-FU.
"
Related Drugs and Biologics
1.
Fluorouracil (Carac)
2.
1-ethoxymethyl-5-fluorouracil
3.
Emitefur
Related Therapies and Procedures
1.
Oral Administration