isophthalate (isophthalic acid)

RN given refers to parent cpd

Also Known As:

isophthalic acid; isophthalate, calcium (1:1)salt; isophthalate, copper (+2) salt; isophthalate, copper (+2) salt (1:1); isophthalate, disodium salt; isophthalate, iron (+2) salt; isophthalate, iron (+2) salt (1:1)

Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - isophthalate: 13

Experts

1.	Talman, Virpi: 4 articles (01/2022 - 05/2014)
2.	Tuominen, Raimo K: 3 articles (01/2022 - 05/2014)
3.	Jäntti, Maria H: 2 articles (01/2022 - 05/2018)
4.	Tarvainen, Ilari: 2 articles (01/2022 - 05/2018)
5.	Nunn, Rebecca C: 1 article (01/2022)
6.	Easton, Julia: 1 article (01/2020)
7.	Pohjolainen, Lotta: 1 article (01/2020)
8.	Ruskoaho, Heikki: 1 article (01/2020)
9.	Solanki, Reesha: 1 article (01/2020)
10.	Ashbrook, Sharon E: 1 article (09/2019)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 05/01/2018 - "In this study, we have characterized the effects of the most potent isophthalate, 5-(hydroxymethyl)isophthalate 1a3 (HMI-1a3), on three prostate cancer cell lines (LNCaP, DU145, and PC3) using both 2D and 3D cell culture models. " 01/01/2022 - "Our group has developed protein kinase C (PKC)-modulating isophthalic acid derivatives that induce cytotoxicity toward human cervical and prostate cancer cell lines. "
2.	Dehydration (Water Stress) 09/01/2019 - "This work presents a study of a series of structurally analogous metal-organic frameworks (MOFs) based on 5-substituted isophthalate linkers and Cu(II) paddlewheel dimers, of interest owing to their "crumple zone" structural rearrangement on dehydration/rehydration. "
3.	Neoplasms (Cancer) 07/01/2023 - "One-step photocatalytic synthesis of Fe3O4@polydiallyl isophthalate magnetic microspheres for magnetocaloric tumor ablation and its potential for tracing on MRI and CT." 02/22/2023 - "In general, tumor cell cultures were more sensitive to isophthalic acid derivatives than to terephthalic acid ones. "
4.	Contracture 09/01/1992 - "Single electrically stimulated (0.2 Hz) adult rat cardiac myocytes loaded with Na(+)-sensitive benzofuran isophthalate (SBFI), the new fluorescent probe, were exposed to glucose-free hypoxia (PO2 less than 0.02 mm Hg), and SBFI fluorescence was monitored to index changes in [Na+]i. Parallel experiments were performed with indo-1-loaded cells to index [Ca2+]i. The SBFI fluorescence ratio (excitation, 350/380 nm) rose significantly during hypoxia after the onset of ATP-depletion contracture, consistent with a rise in [Na+]i. At reoxygenation, the ratio fell rapidly toward baseline levels. " 08/27/1997 - "Verapamil, flunarizine, bepridil (which attenuated the lysophosphatidylcholine-induced Ca2+ overload) and nicardipine (which did not) inhibited the veratridine-induced increase in the concentration of intracellular Na+ (indicated by the increase in fluorescence ratio of Na(+)-binding benzofuran isophthalate) and cell contracture, whereas diltiazem did not. "
5.	Leprosy (Hansen's Disease) 04/01/1963 - "Chemotherapy of leprosy with diethyl- dithiol-isophthalate 'etisul'."

Related Drugs and Biologics

1.	Metal-Organic Frameworks
2.	Protein Kinase C
3.	benzofuran
4.	Endothelin-1 (Endothelin 1)
5.	Bepridil (Vascor)
6.	Veratridine
7.	Verapamil (Calan)
8.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9.	Sodium
10.	Silver

Related Therapies and Procedures

1.	Fluid Therapy (Oral Rehydration Therapy)
2.	Microspheres (Microsphere)
3.	Drug Therapy (Chemotherapy)