HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

HDL cholesteryl ester

cholesteryl esters in HDL can be used as steroidogenic substrate by the rat adrenal cortex

Also Known As:

HDL cholesterol ester

Networked: 19 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Mo, Zhong-Cheng: 1 article (01/2018)
2.	Ou, Han-Xiao: 1 article (01/2018)
3.	Peng, Xiao-Shan: 1 article (01/2018)
4.	Qi, Hui-Zhou: 1 article (01/2018)
5.	Ren, Kun: 1 article (01/2018)
6.	Yi, Guang-Hui: 1 article (01/2018)
7.	Zeng, Yong-Zhi: 1 article (01/2018)
8.	Zhang, Qing-Hai: 1 article (01/2018)
9.	Zhao, Guo-Jun: 1 article (01/2018)
10.	Zheng, Zhi: 1 article (01/2018)

Related Diseases

1.	Shock 01/01/2008 - "In this study, we show that scavenger receptor B-I (SR-BI), an HDL receptor that mediates HDL cholesterol ester uptake into cells, is required for the normal antiinflammatory response to LPS-induced endotoxic shock. "
2.	Atherosclerosis 01/01/2018 - "We aimed to investigate the molecular mechanisms by which miR-24 participates in SR-BI-mediated selective HDL cholesteryl ester (HDL-CE) uptake and further atherogenesis in apoE-/- mice. " 08/01/2013 - "As expected, HDL cholesteryl ester uptake was impaired in Ldlr (-/-) Scarb1 (I179N) mice compared to Ldlr (-/-) control mice, with a net effect of increased small and very small LDL cholesterol in Ldlr (-/-) Scarb1 (I179N) mice being the most probable cause of the observed increased atherosclerosis. " 06/19/2015 - "Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake." 02/01/2001 - "Cholesteryl ester transfer protein (CETP) plays a controversial role in atherogenesis by contributing to the net transfer of high density lipoprotein (HDL) cholesteryl ester (CE) to the liver via apolipoprotein-B-containing lipoproteins (apoB-LP). "
3.	Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency) 03/01/1988 - "The normalization of the HDL cholesteryl ester percentage induced by incubation with purified normal LCAT also was accompanied by an increase in the size of the original fish eye disease HDL particles, which had a mean mass of 115 kd, to HDL particle populations with mean particle masses ranging from 130-220 kd, depending on the concentration of purified LCAT in the incubate. " 01/01/1987 - "The observed normalization of both HDL cholesteryl ester percentage and particle size by lipoprotein depleted pig plasma which contains virtually no cholesteryl ester transfer activity indicates that the latter is not a requisite for esterification of the free cholesterol of fish eye disease HDL."
4.	Type 2 Diabetes Mellitus (MODY) 09/01/1998 - "HDL cholesteryl ester was negatively related to CET (P= 0.017), HL activity (P = 0.033) and NIDDM (P = 0.047) and positively to LCAT activity levels (P = 0.034, multiple r = 0.68). " 05/18/2012 - "Furthermore, in the isolated HDL; HDL-phospholipid and HDL-cholesterol ester content were higher in HNF1A-MODY, than in Type 2 diabetes (1.59 vs. 1.33 mmol/L, p = 0.04 and 1.10 vs. 0.83 mmol/L, p = 0.019, respectively), but were similar to controls (1.59 vs. 1.45 mmol/L, p = 0.35 and 1.10 vs. 1.21 mmol/L, p = 0.19, respectively). " 09/01/1998 - "Plasma cholesteryl ester transfer appears to be a determinant of HDL cholesteryl ester, but other factors are likely to contribute to lower HDL cholesteryl ester levels in NIDDM."
5.	Coronary Disease (Coronary Heart Disease) 06/01/2006 - "Cholesteryl ester transfer protein mediates direct HDL cholesteryl ester delivery to the liver cells; adipose tissue-specific overexpression of cholesteryl ester transfer protein in mice reduces the plasma HDL cholesterol concentration and adipocyte size; cholesteryl ester transfer protein TaqIB polymorphism is associated with HDL cholesterol plasma levels and the risk of coronary heart disease. " 08/30/2017 - "The SCARB1 gene encodes human scavenger receptor class B type I (SR-BI), the primary receptor for high-density lipoprotein (HDL)- cholesteryl ester uptake, and polymorphisms in this gene may influence SR-BI protein expression and serum lipid levels, modulating susceptibility to coronary heart disease (CHD) and cerebral infarction (CI). "

Related Drugs and Biologics

1.	Scavenger Receptors (Scavenger Receptor)
2.	high density lipoprotein receptors
3.	HDL Lipoproteins
4.	Cholesterol Ester Transfer Proteins
5.	HDL Cholesterol
6.	Cholesterol Esters (Cholesteryl Esters)
7.	Apolipoproteins B (ApoB)
8.	Apolipoprotein A-I (Apolipoprotein A1)
9.	Triglycerides (Triacylglycerol)
10.	Phospholipids (Phosphatides)