|1.||Kakuta, Hiroki: 2 articles (01/2011 - 12/2010)|
|2.||Thanasekaran, Pounraj: 1 article (12/2014)|
|3.||Sathish, Veerasamy: 1 article (12/2014)|
|4.||Lu, Zong-Zhan: 1 article (12/2014)|
|5.||Babu, Eththilu: 1 article (12/2014)|
|6.||Rajagopal, Seenivasan: 1 article (12/2014)|
|7.||Ramdass, Arumugam: 1 article (12/2014)|
|8.||Velayudham, Murugesan: 1 article (12/2014)|
|9.||Lu, Kuang-Lieh: 1 article (12/2014)|
|10.||Jung, Jae-Kyung: 1 article (01/2014)|
|1.||Breast Neoplasms (Breast Cancer)
02/01/2008 - "Taken together, our study establishes the first I3C structure-activity relationship for cytostatic activities, and implicates I3C-based N-alkoxy derivatives as a novel class of potentially more potent experimental therapeutics for breast cancer."
02/01/2008 - "N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells."
01/01/2014 - "Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells."
02/01/2008 - "Analysis of growth and cell cycle arrest of indole-treated human breast cancer cells revealed a striking increase in efficacy of the N-alkoxy I3C derivatives that is significantly enhanced by the presence of increasing carbon lengths of the N-alkoxy substituents. "
|2.||Parasitic Diseases (Parasitic Disease)
01/01/2014 - "However, ERα-positive cell lines demonstrated the greatest sensitivity to the anti-tumor effects of I3C and its more potent N-alkoxy derivatives. "
01/01/1955 - "[Alkoxy derivatives of benzyl, di-(beta-chloroethyl), amine in experimental chemotherapy of neoplasms]."
01/01/2014 - "ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment."
10/01/2006 - "Structurally, the new analogues are symmetrical 1,5-diarylpentadienone whose aromatic rings possess an alkoxy substitution at each of the positions 3 and 5. Analysis of the effects of the analogues on the expression of cancer-related genes usually affected by curcumin indicated that some induced the down-regulation of beta-catenin, Ki-ras, cyclin D1, c-Myc, and ErbB-2 at as low as one eighth the concentration at which curcumin normally has an effect. "
02/01/2004 - "Based on these results, various N-cbz-alpha-amino-N-alkoxyglutarimides, where the imide N-H was substituted with the hydroxy and alkoxy group, were prepared and evaluated for their anticonvulsant activities using the Maximal electroshock seizure (MES) and Pentylenetetrazole induced seizure (PTZ) tests and also the rotorod test. "
04/01/1981 - "A selected group of alkoxy- and halogen-substituted 5-benzylidino- and 5-benzylhydantoins was prepared and screened for anticonvulsant activity as measured by the ability of the compound to prevent maximal electroshock and metrazol-induced threshold clonic seizures in rats. "
|5.||tert-Butyl Alcohol (tert-Butanol)
|2.||Drug Therapy (Chemotherapy)