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FLM 5011

Also Known As:

FLM-5011; 2-Hydroxy-5-methyl-laurophenone Oxime

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Lauric Acids: 8
    - FLM 5011: 4
Organic Chemicals: 133
- Amines: 4871
  - Hydroxylamines: 16
    - Oximes: 1292
      - FLM 5011: 4

Experts

1.	Fitzl, G: 1 article (03/2000)
2.	Mark, B: 1 article (03/2000)
3.	Welt, K: 1 article (03/2000)

Related Diseases

1.	Reperfusion Injury 03/01/2000 - "Lipoxygenase inhibitor FLM 5011, an effective protectant of myocardial microvessels against ischemia-reperfusion injury? " 03/01/2000 - "The lipoxygenase inhibitor FLM 5011 was used for protection of the coronary microcirculation against ischemia/ reperfusion injury after ligation of the left coronary artery in dogs. "
2.	Shock 01/01/1988 - "In a well defined endotoxin (ET) shock model we compared the influence of a selective LOX-inhibitor FLM 5011 and the COX-inhibitor Acetylsalicylic acid (ASA) on survival as well as on their effects on TXB2 and 6-oxo-PGF1 and on selected parameters characterizing the shock syndrome. "
3.	Myocarditis (Carditis) 01/01/1988 - "In preliminary investigations on patients with severe active myocarditis impressive clinical and histological improvements after administration of FLM 5011 have been obtained, suggesting an antiinflammatory effect of the substance. " 01/01/1988 - "Antiinflammatory effect of a lipoxygenase inhibitor (FLM 5011) in severe active myocarditis."
4.	Ischemia 05/01/1999 - "Lipoxygenase inhibitor FLM 5011 was used in experimental ischemia and reperfusion with dogs to investigate its ultrastructure-preserving effects on the mitochondria of myocardium. "
5.	Edema (Dropsy) 03/01/2000 - "FLM 5011 treatment reduced the endothelial edema, blebbing and occurrence of pericapillary debris and stabilized the number of vesicles. "

Related Drugs and Biologics

1.	Lipoxygenase Inhibitors
2.	Endotoxins
3.	Aspirin (Acetylsalicylic Acid)

Related Therapies and Procedures

1.	Ligation