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A 1110U

Also Known As:

5-((dimethylamino)thiocarbonyl)thiocarbonohydrazone; A-1110U; A1110U

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrazines: 379
  - Hydrazones: 500
    - A 1110U: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - A 1110U: 2

Related Diseases

1.	Infections 02/01/1991 - "Topical treatment of infections induced by either wild-type (wt) HSV-1 or wt HSV-2 with 3% A1110U in combination with 5% ACV resulted in synergistic (P less than 0.01) reductions in lesion scores. " 02/01/1991 - "These results provide encouragement that the combination of A1110U and ACV may offer an effective therapy for topical treatment of cutaneous HSV infections in humans."
2.	Herpes Simplex 02/01/1989 - "2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir."
3.	Exanthema (Rash) 02/01/1991 - "Synergistic topical therapy by acyclovir and A1110U for herpes simplex virus induced zosteriform rash in mice."

Related Drugs and Biologics

1.	Acyclovir (Aciclovir)
2.	Ribonucleotide Reductases (Ribonucleotide Reductase)
3.	2-acetylpyridine

Related Therapies and Procedures

1.	Therapeutics