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hemoglobin Monroe

Arg replaced by Thr at position 30 on beta chain; variant associated with beta-thalassemia

Also Known As:

Hb Monroe; Hemoglobin Monroe

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Monroe: 3
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Monroe: 3

Experts

1.	Galehdari, Hamid: 1 article (09/2013)
2.	Hamid, Mohammad: 1 article (09/2013)
3.	Kaikhaei, Bijan: 1 article (09/2013)
4.	Mohammadi-Anaei, Marziye: 1 article (09/2013)
5.	Saberi, Alihossein: 1 article (09/2013)
6.	Shariati, Gholamreza: 1 article (09/2013)

Related Diseases

1.

beta-Thalassemia (Cooley's Anemia)

03/01/1998 - "HB S-HB Monroe; a sickle cell-beta-thalassemia syndrome."
01/01/1989 - "Hb Monroe or alpha 2 beta 230(B12)Arg----Thr, a variant associated with beta-thalassemia due to A G----C substitution adjacent to the donor splice site of the first intron."
09/01/2013 - "Identification of IVS-I (-1) (G > C) or Hb Monroe as a report on the beta-globin gene with a beta-thalassemia minor phenotype in south of Iran."
09/01/2013 - "Polymerase chain reaction (PCR) followed by sequencing of the beta-globin gene confirmed the presence of Hb Monroe in the heterozygous form which causes beta-thalassemia due to missplicing in the course of mRNA processing. "

Related Drugs and Biologics

1.	beta-Globins (beta Globin)
2.	Messenger RNA (mRNA)