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boron tetraphenylporphyrin

for use in neutron capture therapy

Also Known As:

BTPP

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ao, Ningjian: 1 article (11/2021)
2.	Lei, Qiqi: 1 article (11/2021)
3.	Li, Riwang: 1 article (11/2021)
4.	Zhang, Hong: 1 article (11/2021)
5.	Zhang, Wenning: 1 article (11/2021)
6.	Zhang, Yuwei: 1 article (11/2021)

Related Diseases

1.	Glioma (Gliomas) 09/01/1990 - "In this study, the uptake of boron was measured in human gliomas xenografted subcutaneously to athymic nude mice in which BTPP was infused intraperitoneally or subcutaneously or both for 3 or 7 days by using similar minipumps. " 09/01/1990 - "Glioma boron concentrations were increased by approximately 80% on the average (up to 33 micrograms/g) when correspondingly greater amounts of BTPP were infused in only 3 days. " 09/01/1990 - "Bulk concentrations of boron up to 18 micrograms/g of glioma and up to 45 micrograms/g of carcinoma were observed when up to 102 micrograms/g of tissue was present in the liver after 7 days of BTPP infusion. "
2.	Carcinoma (Carcinomatosis) 09/01/1990 - "Preliminary studies showed that BTPP accumulates in liver and in a syngeneic ovarian carcinoma, but not in normal brain parenchyma, of mice infused with BTPP subcutaneously for 6 or 7 days via surgically implanted osmotic minipumps. " 09/01/1990 - "Bulk concentrations of boron up to 18 micrograms/g of glioma and up to 45 micrograms/g of carcinoma were observed when up to 102 micrograms/g of tissue was present in the liver after 7 days of BTPP infusion. "
3.	Wounds and Injuries (Trauma) 11/15/2021 - "In view of this concern, a multi-functional polyvinyl alcohol (PVA)/sodium alginate-dopamine (SA-DA) hydrogel matrix-based wound dressing embedding with bis-quaternary triphenyl-phosphonium salt (BTPP+), that would present long-term intrinsic antimicrobial properties was developed using freeze-thawing (F-T) method herein. "
4.	Thrombocytopenia (Thrombopenia) 09/01/1990 - "Cell counts and chemical tests on blood samples from individual mice indicate that BTPP causes moderate hepatotoxicity and thrombocytopenia. "
5.	Neoplasms (Cancer) 09/01/1990 - "This hepatohematic toxicity syndrome should be taken into account if BTPP or a similar agent is used for boron neutron-capture therapy (BNCT) of human malignancies."

Related Drugs and Biologics

1.	Boron
2.	Hydrogels
3.	Salts
4.	Polyvinyl Alcohol
5.	Dopamine (Intropin)
6.	Alginates

Related Therapies and Procedures

1.	Boron Neutron Capture Therapy