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leinamycin (DC 107)

a thiazole containing macrolide characterized by an unusual 1,3-dioxo-1,2-dithiolane moiety that is spiro fused to an 18 member macrolactam ring; isolated from Streptomyces; MF C22-H26-N2-O6-S3; possible DNA alkylator; the leinamycin biosynthetic gene cluster from Streptomyces atroolivaceus S-140 consists of two polyketide synthases genes
Also Known As:
DC 107; DC-107
Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Sun, Daekyu: 3 articles (01/2013 - 08/2004)
2. Gates, Kent S: 2 articles (01/2013 - 05/2008)
3. Rajapakse, Anuruddha: 1 article (01/2013)
4. Keerthi, Kripa: 1 article (01/2013)
5. Gates, Kent: 1 article (01/2010)
6. Viswesh, Velliyur: 1 article (01/2010)
7. Sivaramakrishnan, Santhosh: 1 article (05/2008)
8. Vecsernyés, Miklós: 1 article (09/2006)
9. Fenyvesi, Ferenc: 1 article (09/2006)
10. Herczegh, Pal: 1 article (09/2006)

Related Diseases

1. Carcinoma (Carcinomatosis)
2. Neoplasms (Cancer)
3. Pancreatic Neoplasms (Pancreatic Cancer)

Related Drugs and Biologics

1. Fluorescent Dyes (Fluorescent Probes)
2. DNA (Deoxyribonucleic Acid)
3. O-(biotinylcarbazoylmethyl)hydroxylamine
4. S-deoxyleinamycin
5. KF 22678