DWA 2114

Also Known As:

1,1-cyclobutanedicarboxylato(2-aminomethylpyrrolidine)platinum(II); 2-aminomethylpyrrolidine(1,1-cyclobutanedicarboxylatato)platinum II; DW A 2114R; DWA 2114R; DWA-2114; DWA-2114R; Platinum, (1,1-cyclobutanedicarboxylato(2-))(2-pyrrolidinemethanamine-Nalpha,N1)-, (SP-4-3-(R))-

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Coordination Complexes: 576
  - Carboplatin: 10368
    - DWA 2114: 4

Related Diseases

1.	Neoplasms (Cancer) 01/01/1990 - "These results suggest that DWA 2114 R seemed to be more effective against CDDP-resistant tumors clinically than CDDP and CBDCA." 01/01/1990 - "Antitumor activity of a new platinum complex, (R)-(-)-2-aminomethylpyrrolidine (1, 1-cyclobutanedicarboxylato) platinum (II) (DWA 2114 R) against cisdiamminedichloroplatinum (II) (CDDP)-resistant tumor was examined in in vitro and in vivo experiments. " 07/01/1989 - "We evaluated the inhibitory effects of DWA 2114 on other tumors, such as Colon 38 carcinoma, Ca 755 mammary adenocarcinoma and L1210 leukemia, and found that it also had antitumor effects on various kinds of tumors. " 07/01/1992 - "A phase I study on a weekly schedule of DWA 2114R, a new platinum analogue, was conducted in 21 patients with various tumor types by clinical groups at 10 institutions. " 06/01/1991 - "When the antitumor activity of KB-5424 was evaluated using several rodent tumors, no significant differences were observed between the antitumor activities of KB-5424, cisplatin (CDDP) and DWA-2114 R (DWA). "
2.	Leukemia L1210 07/01/1989 - "We evaluated the inhibitory effects of DWA 2114 on other tumors, such as Colon 38 carcinoma, Ca 755 mammary adenocarcinoma and L1210 leukemia, and found that it also had antitumor effects on various kinds of tumors. "
3.	Carcinoma (Carcinomatosis) 07/01/1989 - "We evaluated the inhibitory effects of DWA 2114 on other tumors, such as Colon 38 carcinoma, Ca 755 mammary adenocarcinoma and L1210 leukemia, and found that it also had antitumor effects on various kinds of tumors. "
4.	Adenocarcinoma 07/01/1989 - "We evaluated the inhibitory effects of DWA 2114 on other tumors, such as Colon 38 carcinoma, Ca 755 mammary adenocarcinoma and L1210 leukemia, and found that it also had antitumor effects on various kinds of tumors. "

Related Drugs and Biologics

1.	Carboplatin (JM8)
2.	Platinum
3.	Dihydrotachysterol (AT 10)
4.	Cisplatin (Platino)
5.	KB 5424