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fibrolase

from the venom of Agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; MW 23-25kDa; cleaves primarily the Aa-chain of human fibrinogen & fibrin between the Lys-413 & Leu-414 position; the Bb chain is cleaved more slowly; gamma chain is minimally affected
Also Known As:
Agkistrodon contortrix fibrin-degrading metalloprotease
Networked: 6 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Swenson, Steve: 1 article (04/2010)
2. Markland, Francis S: 1 article (04/2010)
3. Toombs, C F: 1 article (12/2004)
4. Pena, L: 1 article (12/2004)
5. Johansson, J: 1 article (12/2004)
6. Swenson, S: 1 article (12/2004)
7. Markland, F S: 1 article (12/2004)

Related Diseases

1. Thrombosis (Thrombus)
2. Hemorrhage
3. Stroke (Strokes)
4. Venous Thrombosis (Deep-Vein Thrombosis)
5. Carotid Artery Thrombosis

Related Drugs and Biologics

1. Anistreplase (APSAC)
2. Recombinant DNA (Recombinant DNA Research)
3. alfimeprase
4. arginyl-glycyl-aspartic acid

Related Therapies and Procedures

1. Catheters