sarcophytol A

11/01/1991 - "These results suggest that sarcophytol A inhibits the development of spontaneous hepatomas without toxicity, and should be considered as a possible cancer chemopreventive agent for hepatomas in humans."
11/01/1991 - "The percentages of hepatoma-bearing mice of the subgroup with three or more tumors and the tumor diameters of the group treated with sarcophytol A were smaller than those of the control group. "
08/01/1993 - "Since canventol is less toxic to cells than sarcophytol A, these bifunctions are useful markers for screening for new cancer chemopreventive agents."
01/01/1992 - "Preincubation of the lens with anti-tumor promoting agents EGCG (epigallocatechin gallate) or Sarp A (sarcophytol A) stopped the TPA-mediated opacification process and suppressed H2O2 elevation."
06/15/1989 - "Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum."

06/15/1989 - "An antitumorigenic effect of sarcophytol A (SaA), a simple monohydroxycembratetraene isolated from a marine soft coral Sarcophyton glaucum, was investigated in rat colon carcinogenesis. "
08/01/1996 - "Inhibitory effect of sarcophytol A on pancreatic carcinogenesis after initiation by N-nitrosobis(2-oxypropyl)amine in Syrian hamsters."
08/01/1996 - "Sarcophytol A (SaA), a cembrane-type diterpene, inhibits pancreatic carcinogenesis induced by N-nitrosobis(2-oxypropyl)amine (BOP) in hamsters. "
08/01/1993 - "A synthetic compound named canventol, 2-isopropyl-4-isopropylidencyclohex-2-ene-1-ol, inhibited tumor promotion of okadaic acid on mouse skin initiated with 7,12-dimethylbenz(a)anthracene in two-stage carcinogenesis experiments more strongly than sarcophytol A, isolated from a soft coral, although canventol has a simpler structure than sarcophytol A. "
08/15/1996 - "Mechanisms of cancer prevention were studied using structurally different cancer-preventive agents, sarcophytol A, canventol, (-)-epigallo-catechin gallate, and tamoxifen, based on our evidence that tumor necrosis factor alpha (TNF-alpha) acts as an endogenous tumor promoter relevant to human carcinogenesis. "

07/01/1994 - "Sarcophytol A: a new chemotherapeutic and chemopreventive agent for pancreatic cancer."

11/01/1991 - "Inhibitory effect of sarcophytol A on development of spontaneous hepatomas in mice."
11/01/1991 - "These results suggest that sarcophytol A inhibits the development of spontaneous hepatomas without toxicity, and should be considered as a possible cancer chemopreventive agent for hepatomas in humans."
11/01/1991 - "The percentages of hepatoma-bearing mice of the subgroup with three or more tumors and the tumor diameters of the group treated with sarcophytol A were smaller than those of the control group. "
11/01/1991 - "The inhibitory effect of sarcophytol A, a cembrane-type diterpene isolated from a marine soft coral, Sarcophyton glaucum, on development of spontaneous hepatomas was investigated in C3H/HeNCrj mice. "