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msDNA

from Myxococcus xanthus & other bacteria; consists of a branched RNA linked to single-stranded DNA via a 2',5'-phosphodiester bond

Also Known As:

multicopy single-stranded DNA

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ahmed, Ashraf M: 1 article (06/2013)
2.	Shimamoto, Tadashi: 1 article (06/2013)
3.	Shimamoto, Toshi: 1 article (06/2013)

Related Diseases

1.	Starvation 08/01/1996 - "Its presence is required for starvation-induced transcription of retron-Ec107 and multicopy single-stranded DNA production. " 08/01/1996 - "Starvation-induced expression of retron-Ec107 and the role of ppGpp in multicopy single-stranded DNA production."
2.	Infections 01/01/2022 - "Consistently, retron toxin-antitoxin systems act as abortive infection anti-phage defence systems, in line with recent reports3,4. Thus, RcaT retrons are tripartite DNA-regulated toxin-antitoxin systems, which use the reverse transcriptase-msDNA complex both as an antitoxin and as a sensor of phage protein activities."
3.	Gastroenteritis 06/01/2013 - "In this report, msDNA from Vibrio parahaemolyticus, a cause of acute gastroenteritis, was identified and named msDNA-Vp96. "

Related Drugs and Biologics

1.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
2.	Proteins (Proteins, Gene)
3.	Guanosine Tetraphosphate
4.	DNA (Deoxyribonucleic Acid)
5.	Antitoxins