05/01/1991 - "Only patients given 0.24 micrograms/kg of pentamorphone experienced decreased pain intensity and increased sedation, both transient in duration. "
03/01/1989 - "Pentamorphone produced a linear increase in pain tolerance with increasing dose as well as a dose-dependent depression of ventilation. "
05/01/1991 - "Pentamorphone (0.08-0.24 micrograms/kg) was ineffective for treating acute postoperative pain after major surgery."
05/01/1991 - "The efficacy, duration, and safety of the synthetic opioid pentamorphone in the treatment of acute postoperative pain were evaluated in a randomized, double-blind study of 72 patients given 0.08, 0.16, or 0.24 micrograms/kg of pentamorphone or a placebo intravenously in the recovery room after major abdominal or orthopedic surgery. "
05/01/1991 - "Pentamorphone for management of postoperative pain."
|3.||Hypotension (Low Blood Pressure)
|4.||Hypertension (High Blood Pressure)
10/01/1990 - "Pentamorphone produced dose-related reductions in the ventilatory responses to both hypercapnia and hypoxia. "
10/01/1990 - "We quantified the effects of pentamorphone (0.08, 0.24, and 0.60 micrograms/kg, IV) on ventilatory responses to hypercapnia and hypoxia in 12 healthy volunteers. "
10/01/1990 - "Depression of ventilatory responses to hypoxia and hypercapnia after pentamorphone."