|1.||Onodera, Satoshi: 8 articles (01/2013 - 12/2004)|
|2.||Ikejima, Takashi: 7 articles (01/2013 - 12/2004)|
|3.||Tashiro, Shin-ichi: 6 articles (01/2013 - 12/2004)|
|4.||Ding, Jian: 3 articles (09/2012 - 12/2004)|
|5.||Yu, Jinghua: 2 articles (11/2015 - 07/2008)|
|6.||Li, Yan: 2 articles (01/2015 - 01/2014)|
|7.||Khan, Shabana I: 2 articles (04/2014 - 09/2010)|
|8.||Khan, Ikhlas A: 2 articles (04/2014 - 09/2010)|
|9.||Walker, Larry A: 2 articles (04/2014 - 09/2010)|
|10.||Wang, Jia-He: 2 articles (02/2014 - 09/2013)|
01/01/2015 - "Pseudolaric acid B is a new diterpene acid compound isolated from pseudolarix, which has been found to have anti-tumor activities in recent studies. "
09/01/2013 - "Numerous studies have demonstrated that pseudolaric acid B (PAB) promotes apoptosis in several cancer cell lines. "
06/01/2013 - "Previous studies have shown that Pseudolaric acid B (PAB), a medicinal plant-derived terpenoid, is a promising chemopreventive or therapeutic agent against various types of cancer. "
08/01/2015 - "Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of the root and trunk of Pseudolarix kaempferi Gordon (Pinaceae), which has demonstrated cytotoxic effects against various types of cancer. "
08/01/2015 - "Pseudolaric acid B exerts antitumor activity via suppression of the Akt signaling pathway in HeLa cervical cancer cells."
|2.||Melanoma (Melanoma, Malignant)
04/01/2009 - "The aim of this study was to investigate the mechanism of pseudolaric acid B (PLAB)-induced cell cycle arrest in human melanoma SK-28 cells. "
01/01/2005 - "In our study, pseudolaric acid B inhibited growth of human melanoma cells, A375-S2 in a time- and dose-dependent manner. "
01/01/2005 - "Pseudolaric acid B induces apoptosis through p53 and Bax/Bcl-2 pathways in human melanoma A375-S2 cells."
01/01/2005 - "[Pseudolaric acid B induces human melanoma A375-S2 cell apoptosis in vitro]."
11/01/2012 - "To study the effect of pseudolaric acid B (PLAB) on cell proliferation and cycle of human prostate carcinoma DU-145 cells. "
07/01/2010 - "[Study on the apoptosis inducing effect of pseudolaric acid B on cervical carcinoma cell line HeLa cells]."
11/01/2012 - "[Cycle arrest of prostate carcinoma DU-145 cells induced by pseudolaric acid B]."
01/01/2009 - "Pseudolaric acid B-induced apoptosis through p53-dependent pathway in human gastric carcinoma cells."
|4.||Stomach Neoplasms (Stomach Cancer)
01/01/2015 - "The purpose of the present study was to evaluate the effects of pseudolaric acid B in an MDR gastric cancer cell line and elucidate the possible underlying mechanisms of action. "
12/28/2005 - "To examine the effect of pseudolaric acid B on the growth of human gastric cancer cell line, AGS, and its possible mechanism of action. "
12/28/2005 - "Effect of pseudolaric acid B on gastric cancer cells: inhibition of proliferation and induction of apoptosis."
01/01/2015 - "Pseudolaric acid B circumvents multidrug resistance phenotype in human gastric cancer SGC7901/ADR cells by downregulating Cox-2 and P-gp expression."
01/01/2014 - "The inhibitory effect of pseudolaric acid B on gastric cancer and multidrug resistance via Cox-2/PKC-α/P-gp pathway."
08/01/2012 - "We have recently discovered that c-Jun executes a non-transcriptional function to stabilize hypoxia inducible factor 1α (HIF-1α) and that pseudolaric acid B (PAB) accelerates HIF-1α degradation and phosphorylates c-Jun at Ser63/73. "
09/01/2012 - "In particular, through studies on the antiangiogenic mechanism of pseudolaric acid B, we discovered a novel mechanism by which the stability of hypoxia-inducible factor 1α is regulated by the transcription factor c-Jun. "
12/15/2004 - "Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation."
|1.||Transcription Factors (Transcription Factor)
|3.||Proteasome Endopeptidase Complex (Proteasome)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)