naloxone benzoylhydrazone

structure given in first source

Also Known As:

6-desoxy-6-benzoylhydrazido-N-allyl-14-hydroxydihydronormorphinone; NalBzoH; Benzoic acid, ((5alpha)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene)hydrazide

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hryniewicz, A: 1 article (09/2001)
2.	Koneczny, B: 1 article (09/2001)
3.	Malinowska, B: 1 article (09/2001)
4.	Piszcz, J: 1 article (09/2001)
5.	Schlicker, E: 1 article (09/2001)
6.	Altememi, G F: 1 article (02/2001)
7.	Mandyam, C D: 1 article (02/2001)
8.	Mathis, J P: 1 article (02/2001)
9.	Pasternak, G W: 1 article (02/2001)
10.	Standifer, K M: 1 article (02/2001)

Related Diseases

1.	Hyperalgesia 07/17/1998 - "Furthermore, behavioral studies demonstrated that NalBzoH completely inhibited nociceptin-induced hyperalgesia and hypolocomotion. " 04/01/1999 - "Further, NalBzoH completely inhibited nociceptin-induced hyperalgesia and hypolocomotion in wild-type mice. "
2.	Hyperphagia (Overeating) 05/29/1992 - "Whereas naltrexone significantly reduced both U50,488H and NalBzoH hyperphagia, Nor-BNI blocked U50,448H, but not NalBzoH hyperphagia. " 03/01/1997 - "Whereas hyperphagia elicited by the kappa1 receptor agonist, U50488H is blocked by general and kappa1 opioid antagonists, hyperphagia elicited by the kappa3 receptor agonist, naloxone benzoylhydrazone (NalBzOH) is blocked by general, but not kappa1 opioid antagonists. "
3.	Tachycardia (Tachyarrhythmias) 09/01/2001 - "The OP4 receptor antagonists naloxone benzoylhydrazone 5 micromol/kg and/or [Phe1Psi(CH2-NH)Gly2]-nociceptin(1-13)NH2 0.7 micromol/kg, but not the OP(1-3) receptor antagonist naloxone 10 micromol/kg, diminished the inhibitory action of nociceptin on the neurogenic tachycardia and bradycardia. "
4.	Neuroblastoma 02/23/2001 - "Orphanin FQ/nociceptin and naloxone benzoylhydrazone activate distinct receptors in BE(2)-C human neuroblastoma cells."
5.	Bradycardia 09/01/2001 - "The OP4 receptor antagonists naloxone benzoylhydrazone 5 micromol/kg and/or [Phe1Psi(CH2-NH)Gly2]-nociceptin(1-13)NH2 0.7 micromol/kg, but not the OP(1-3) receptor antagonist naloxone 10 micromol/kg, diminished the inhibitory action of nociceptin on the neurogenic tachycardia and bradycardia. "

Related Drugs and Biologics

1.	Nociceptin
2.	(trans)-Isomer 3,4- Dichloro- N- methyl- N- (2- (1- pyrrolidinyl)- cyclohexyl)- benzeneacetamide
3.	naloxone benzoylhydrazone
4.	Narcotic Antagonists (Opioid Antagonists)
5.	Naltrexone (ReVia)
6.	Naloxone (Narcan)
7.	norbinaltorphimine