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mitochondrial RNA-processing endoribonuclease (RNAse MRP)

Also Known As:

RNAse MRP; 7-2-MRP; 7-2-MRP RNAse; ribonuclease MRP

Networked: 42 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Ribonucleases: 2046
        Endoribonucleases: 176
        mitochondrial RNA-processing endoribonuclease: 42
      - Endonucleases: 1227
        Endoribonucleases: 176
        mitochondrial RNA-processing endoribonuclease: 42

Experts

1.	Welting, Tim J M: 5 articles (12/2021 - 03/2008)
2.	Zabel, Bernhard: 4 articles (12/2021 - 11/2005)
3.	Caron, Marjolein M J: 3 articles (12/2021 - 01/2017)
4.	Friedrich, Franziska: 3 articles (12/2021 - 01/2017)
5.	Surtel, Don A M: 3 articles (12/2021 - 01/2017)
6.	van Rhijn, Lodewijk W: 3 articles (12/2021 - 01/2017)
7.	Pruijn, Ger J M: 3 articles (01/2017 - 03/2008)
8.	Lausch, Ekkehart: 2 articles (12/2021 - 01/2017)
9.	Peffers, Mandy J: 2 articles (12/2021 - 01/2019)
10.	van den Akker, Guus G H: 2 articles (12/2021 - 01/2019)

Related Diseases

1.	Carcinogenesis 06/21/2016 - "Because the RNA component of mitochondrial RNA processing endoribonuclease (RMRP) is one of the dysregulated lncRNAs in gastric cancer, this study explored its molecular mechanisms in carcinogenesis. " 10/01/2021 - "Long Noncoding-RNA Component of Mitochondrial RNA Processing Endoribonuclease Promotes Carcinogenesis in Triple-Negative Breast Cancer Cells via the Competing Endogenous RNA Mechanism." 01/01/2019 - "LncRNA RMRP (RNA component of mitochondrial RNA processing endoribonuclease) has been proved to involve in the tumorigenesis of several human cancers. "
2.	Anauxetic dysplasia 01/01/2019 - "Cartilage hair hypoplasia (CHH), anauxetic dysplasia 1, and anauxetic dysplasia 2 are rare metaphyseal dysplasias caused by biallelic pathogenic variants in RMRP and POP1, which encode the components of RNAse-MRP endoribonuclease complex (RMRP) in ribosomal biogenesis pathway. " 11/01/2005 - "Anauxetic dysplasia mutations thus lead to poor processing of ribosomal RNA while allowing normal mRNA processing and, therefore, genetically separate the different functions of RNase MRP." 03/01/2011 - "Our studies identified two novel compound heterozygous loss-of-function mutations in POP1, which encodes a core component of the RNase mitochondrial RNA processing (RNase MRP) complex that directly interacts with the RMRP RNA domains that are affected in anauxetic dysplasia. "
3.	Breast Neoplasms (Breast Cancer) 01/01/2021 - "LncRNA RNA Component of Mitochondrial RNA-Processing Endoribonuclease Promotes AKT-Dependent Breast Cancer Growth and Migration by Trapping MicroRNA-206." 01/01/2023 - "In order to find the underlying mechanism of dysregulation of Tregs in breast cancer tissues, we designed the current study to appraise expression of five Treg-related long non-coding RNAs (lncRNAs), namely FLICR (FOXP3 Regulating Long Intergenic Non-Coding RNA), NEST (IFNG-AS1), RMRP (RNA Component of Mitochondrial RNA Processing Endoribonuclease), MAFTRR (MAF Transcriptional Regulator RNA) and TH2-LCR (Th2 Cytokine Locus Control Region) in paired breast cancer and nearby noncancerous tissues. "
4.	Wounds and Injuries (Trauma) 11/10/2021 - "The present study aimed to explore the role of RNA component of mitochondrial RNA-processing endoribonuclease (RMRP) in the effects of human umbilical vein endothelial cell (HUVEC)-derived exosomes on ischemic injuries in vitro and in vivo. " 11/10/2021 - "Exosomes from Human Umbilical Vein Endothelial Cells Ameliorate Ischemic Injuries by Suppressing the RNA Component of Mitochondrial RNA-processing Endoribonuclease via the Induction of miR-206/miR-1-3p Levels."
5.	Stomach Neoplasms (Stomach Cancer) 06/21/2016 - "Because the RNA component of mitochondrial RNA processing endoribonuclease (RMRP) is one of the dysregulated lncRNAs in gastric cancer, this study explored its molecular mechanisms in carcinogenesis. "

Related Drugs and Biologics

1.	RNA (Ribonucleic Acid)
2.	Long Noncoding RNA
3.	Ribonucleases (Ribonuclease)
4.	Messenger RNA (mRNA)
5.	Untranslated RNA (Noncoding RNA)
6.	Mitochondrial RNA
7.	RNA-Binding Proteins (RNA-Binding Protein)
8.	Cytokines
9.	Small Nucleolar RNA (snoRNA)
10.	Proteins (Proteins, Gene)