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2-phenylpyridine

structure given in first source

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 2-phenylpyridine: 7

Experts

1.	Liu, Zhe: 2 articles (01/2020 - 06/2011)
2.	El-Mehasseb, I M: 2 articles (12/2001 - 03/2001)
3.	Kodaka, M: 2 articles (12/2001 - 03/2001)
4.	Okada, T: 2 articles (12/2001 - 03/2001)
5.	Okamoto, K: 2 articles (12/2001 - 03/2001)
6.	Okuno, H: 2 articles (12/2001 - 03/2001)
7.	Tomohiro, T: 2 articles (12/2001 - 03/2001)
8.	Aoki, Shin: 1 article (01/2022)
9.	Tsuchiya, Koji: 1 article (01/2022)
10.	Umezawa, Masakazu: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2014 - "In this study, three structurally related cationic Pt complexes, [Pt(ppy)(dppe)]CF3CO2: C1, [Pt(bhq)(dppe)]CF3CO2: C2, and [Pt(bhq)(dppf)]CF3CO2: C3, in which ppy=deprotonated 2-phenylpyridine, bhq=deprotonated benzo[h]quinoline, dppe=bis(diphenylphosphino)ethane and dppf=1,1'-bis(diphenylphosphino)ferrocene, were used for the assessment of their anticancer activities against Jurkat and MCF-7 cancer cell lines. " 01/01/2022 - "We previously reported that a cyclometalated iridium (Ir) complex-peptide hybrid (IPH) 4 functionalized with a cationic KKKGG peptide unit on the 2-phenylpyridine ligand induces paraptosis, a relatively newly found programmed cell death, in cancer cells (Jurkat cells) via the direct transport of calcium (Ca2+) from the endoplasmic reticulum (ER) to mitochondria. "
2.	Sarcoma 180 12/20/2001 - "Mononuclear platinum(II) complex with 2-phenylpyridine ligands showing high cytotoxicity against mouse sarcoma 180 cells acquiring high cisplatin resistance." 03/01/2001 - "A platinum (II) mononuclear complex with two kinds of 2-phenylpyridine which coordinate as cyclometalated and non-chelated ligands shows high cytotoxicity against cisplatin-resistant mouse sarcoma 180 cell in comparison with its related complexes."
3.	Parkinson Disease (Parkinson's Disease) 07/01/1988 - "2-Phenylpyridine and 3-phenylpyridine, constituents of tea, are unlikely to cause idiopathic Parkinson's disease."
4.	Ovarian Neoplasms (Ovarian Cancer) 06/20/2011 - "Replacing the N,N-chelating ligand 2,2'-bipyridine (bpy) in the Ir(III) pentamethylcyclopentadienyl (Cp*) complex [(η(5)-C(5)Me(5))Ir(bpy)Cl](+) (1) with the C,N-chelating ligand 2-phenylpyridine (phpy) to give [(η(5)-C(5)Me(5))Ir(phpy)Cl] (2) switches on cytotoxicity toward A2780 human ovarian cancer cells (IC(50) values of >100 μM for 1 and 10.8 μM for 2). "
5.	Neoplasm Metastasis (Metastasis) 01/01/2020 - "Dual functions of iridium(III) 2-phenylpyridine complexes: Metastasis inhibition and lysosomal damage."

Related Drugs and Biologics

1.	bis(diphenylphosphine)ethane (bis(diphenylphosphino)ethane)
2.	tesmilifene (DPPE)
3.	benzo(h)quinoline
4.	ferrocene
5.	Ligands
6.	Platinum
7.	Iridium
8.	Cisplatin (Platino)
9.	2,2'-Dipyridyl (2,2 Bipyridine)
10.	Tea