arsenic disulfide (realgar)

01/01/2016 - "In previous studies, it was found that realgar NPs can inhibit several types of tumor cell proliferation. "
10/27/2014 - "In the present study, we elucidated antitumor mechanism of Chijongdan, an oriental prescription of Rhus verniciflua, processed Panax ginseng, Persicaria tinctoria and Realgar, that has been traditionally applied for cancer treatment in Korea. "
01/01/2005 - "Our previous studies have demonstrated that realgar nanoparticles may provide a less toxic agent for anti-neoplasia by suppressing angiogenesis. "
07/01/2021 - "These results reveal that Nano-realgar inhibits tumor growth in vitro and in vivo by repressing metabolic reprogramming. "
07/01/2021 - "Nano-realgar inhibits tumor growth and changes the histological structure of tumors through in vivo experiments and consequently inhibits the constitutive activation of HIF-1α signaling. "

12/01/2019 - "(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia."
03/01/2022 - "Realgar was reported to have efficacy for acute promyelocytic leukemia (APL). "
08/01/2002 - "To elucidate the molecular mechanism of realgar-induced apoptosis and differentiation of acute promyelocytic leukemia(APL) cell line NB4. "
03/01/2002 - "To acquire a deep understanding of the possible mechanisms of realgar in the treatment of acute promyelocytic leukemia (APL). "
09/12/2022 - "Realgar (As4S4), a traditional Chinese medicine, induces acute promyelocytic leukemia cell death via the Bcl-2/Bax/Cyt-C/AIF signaling pathway in vitro."

01/01/2005 - "In the present study, we improved milling process, prepared raw realgar particles and realgar nanoparticles with the same background As<inf>2</inf>O<inf>3</inf>concentrations and compared their cytoxcity to promyelocytic leukemia HL-60 cells including inhibiting cell growth, inducing oxidative stress. "
02/01/2014 - "Arsenic disulfide (As₂S₂) has been traditionally used to treat certain types of leukemia. "
07/01/2013 - "Nano-Realgar significantly induced apoptosis of drug-sensitive leukemia cells."
07/01/2013 - "To explore apoptosis-inducing effects of realgar nanoparticle (nano-realgar) on drug-sensitive leukemia cells. "
07/01/2013 - "[Apoptosis effects of drug sensitivity leukemia cells induced by nano-realgar]."

01/01/2020 - "[Corrigendum] Antitumor effects of arsenic disulfide on the viability, migratory ability, apoptosis and autophagy of breast cancer cells."
01/01/2020 - "Wound-healing migration assays and Transwell invasion assays were carried out to determine the effects of nano-realgar on breast cancer cell (4T1) migration and invasion. "
01/01/2019 - "Antitumor effects of arsenic disulfide on the viability, migratory ability, apoptosis and autophagy of breast cancer cells."
01/01/2018 - "Anticancer efficacies of arsenic disulfide through apoptosis induction, cell cycle arrest, and pro-survival signal inhibition in human breast cancer cells."
01/01/2020 - "To explore the inhibitory effects and molecular mechanisms of nano-realgar on the migration, invasion and metastasis of mouse breast cancer cells. "

02/01/2017 - "Realgar transforming solution displays anticancer potential against human hepatocellular carcinoma HepG2 cells by inducing ROS."
01/01/2014 - "Realgar NPs had higher cytotoxicity on the selected cell lines, namely human breast cancer (MCF7), human hepatoma (HepG2), and human lung cancer (A549) cell lines, than coarse realgar. "
01/01/2011 - "In this study, the effects of the size and Chinese traditional processing (including elutriation, water cleaning, acid cleaning, alkali cleaning) on realgar nanoparticles (RN)-induced antitumor activity in human osteosarcoma cell lines (MG-63) and hepatoma carcinoma cell lines (HepG-2) were investigated. "