|1.||Liu, Jie: 6 articles (01/2015 - 01/2003)|
|2.||Zeng, Zhenhua: 5 articles (11/2015 - 01/2014)|
|3.||Chen, Zhongqing: 5 articles (11/2015 - 01/2014)|
|4.||Wang, Xingmin: 5 articles (11/2015 - 04/2012)|
|5.||Li, Tao: 4 articles (11/2015 - 01/2014)|
|6.||Zhao, Ke-seng: 4 articles (09/2015 - 06/2011)|
|7.||Song, Rui: 4 articles (07/2015 - 04/2012)|
|8.||Zhao, Ke-Seng: 4 articles (07/2015 - 01/2003)|
|9.||Zhang, Yi: 4 articles (01/2015 - 04/2008)|
|10.||Xu, Siqi: 3 articles (11/2015 - 01/2015)|
02/01/2008 - "To observe protective effects of polydatin (PD) during lung ischemia/reperfusion injury (LI/RI) and investigate its potential mechanism . "
02/01/2008 - "[Protective effects of polydatin against lung ischemia/reperfusion injury and the initial exploration for its mechanism]."
08/01/2014 - "Increasing number of studies have demonstrated the protective effect of polydatin on renal ischemia reperfusion injury. "
01/01/2015 - "Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway."
09/01/2014 - "Polydatin (PD) has anti-inflammatory and anti-apoptotic effects in ischemic-reperfusion injury. "
09/01/2015 - "Polydatin (PD), a monocrystalline and polyphenolic drug isolated from a traditional Chinese herb (Polygonum cuspidatum), is protective against mitochondrial dysfunction and has been approved for clinical trials in the treatment of shock. "
04/01/2012 - "The main objective of this study was to investigate the activity of polydatin on mitochondrial dysfunction and lysosomal stability of arteriolar smooth muscle cells (ASMCs) in severe shock. "
01/01/2003 - "The study suggests that Polydatin has multiple effects on VSMC, MC, WBC and EC, which are related to the enhancement of heart function and improvement of microcirculatory perfusion in shock."
01/01/2003 - "The aim of this study is to explain the cellular and molecular basis of Polydatin in shock treatment. "
11/01/2015 - "Polydatin (PD), a natural polyphenol, demonstrates protective mitochondrial effects in neurons and arteriolar smooth muscle cells during severe shock. "
02/01/2009 - "To investigate protective effects of polydatin(PD) during lung ischemia/reperfusion in rabbits and its potential mechanisms. "
08/01/2014 - "This study aimed to investigate the effect of polydatin on ischemia-reperfusion induced expression of toll-like receptor4 (TLR4) in rat renal tubular epithelia cells (NRK-52E), and analyze the mechanism of polydatin on TLR4 signal pathway. "
08/25/2009 - "The aim of the present study was to investigate the effect of polydatin on apoptosis induced by ischemia/reperfusion (I/R) in rat myocardium and to explore the underlying mechanism. "
09/19/2006 - "Previous studies have demonstrated that polydatin, a crystal component extracted from the root stem of the perennial herbage Polygonum Cuspidatum Sieb.et Zucc, exerts a neuroprotective effect on cerebral injury induced by ischemia/reperfusion. "
08/25/2009 - "Polydatin attenuates ischemia/reperfusion-induced apoptosis in myocardium of the rat."
01/04/2012 - "Polydatin modulates inflammation by decreasing NF-κB activation and oxidative stress by increasing Gli1, Ptch1, SOD1 expression and ameliorates blood-brain barrier permeability for its neuroprotective effect in pMCAO rat brain."
11/01/2015 - "The inhibition of PI3K/Akt signaling pathway counteracted the anti-inflammation and pro-survival effects of polydatin and blocked the protein expression of Shh in HK-2 cells. "
10/15/2012 - "Polydatin has been shown to have the ability of anti-adhesive inflammation. "
01/01/2012 - "Polydatin may be an effective hepatoprotective agent and a promising candidate for the treatment of oxidative stress- and inflammation-related diseases."
12/01/2011 - "Previous studies revealed that polydatin, a natural small compound, possessed protective effect against ischemia/reperfusion injury and inflammation. "
07/01/2015 - "Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway."
01/01/2015 - "Polydatin Alleviates Small Intestine Injury during Hemorrhagic Shock as a SIRT1 Activator."
02/01/2013 - "Polydatin--a new mitochondria protector for acute severe hemorrhagic shock treatment."
04/01/2012 - "Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock."
06/01/2011 - "Polydatin is an effective drug in ameliorating microcirculatory insufficiency and increasing survival rate in non-pregnant animal model of controlled hemorrhagic shock. "
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|6.||Messenger RNA (mRNA)
|3.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|4.||Combination Drug Therapy (Combination Chemotherapy)