|1.||Bonkovsky, Herbert L: 2 articles (05/2010 - 03/2008)|
|2.||Zheng, Jianyu: 2 articles (05/2010 - 03/2008)|
|3.||Hou, Weihong: 2 articles (05/2010 - 03/2008)|
|4.||Tian, Qing: 1 article (05/2010)|
|5.||Donohue, Susan E: 1 article (03/2008)|
|6.||Lambrecht, Richard W: 1 article (03/2008)|
|7.||Shan, Ying: 1 article (03/2008)|
|8.||Lindberg, R L: 1 article (05/2001)|
|9.||Meyer, U A: 1 article (05/2001)|
|10.||Hoffmann, F: 1 article (05/2001)|
|1.||Hepatic Porphyrias (Hepatic Porphyria)
05/01/2001 - "We conclude that the combined effect of ZnMP on highly induced ALAS and on HO may be of potential benefit for human acute hepatic porphyrias and therefore merits further in vivo investigations addressing questions raised by this study."
05/01/2001 - "Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria."
|2.||Acute Intermittent Porphyria (Porphyria, Acute)
02/01/1995 - "Recent results from our laboratory showed that a combination of heme and zinc-mesoporphyrin was remarkably effective in ameliorating biochemical features of acute porphyria. "
06/01/1994 - "Repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria."
08/01/1994 - "The ability of zinc-mesoporphyrin to supplement the reduction of delta-aminolevulinic acid synthase mRNA by heme, in a process similar to that observed with heme alone, provides a rationale for further investigation of this compound for eventual use as a supplement to heme therapy of the acute porphyrias and perhaps other conditions in which heme may be of benefit."
|3.||Hepatocellular Carcinoma (Hepatoma)
05/01/2010 - "Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells."
05/01/2010 - "Human hepatoma cells expressing HCV proteins were used to investigate the posttranslational regulation of ZnMP on NS5A protein by Western blots and immunoprecipitation. "
03/01/2008 - "To understand how zinc mesoporphyrin (ZnMP) induces the expression of HO-1, we investigated the effects of ZnMP on Bach1 mRNA and protein levels in human hepatoma Huh-7 cells by quantitative RT-PCR and Western blots. "
|2.||Messenger RNA (mRNA)
|4.||Proteins (Proteins, Gene)
|5.||Heme Oxygenase (Decyclizing) (Heme Oxygenase)
|6.||Aminolevulinic Acid (Levulan)